Ynddal L - Search Results

1

Pharmacokinetic-pharmacodynamic modeling of ipamorelin, a growth hormone releasing peptide, in human volunteers.

Gobburu JV, Agersø H, Jusko WJ, Ynddal L. Gobburu JV, et al. Among authors: ynddal l. Pharm Res. 1999 Sep;16(9):1412-6. doi: 10.1023/a:1018955126402. Pharm Res. 1999. PMID: 10496658 Clinical Trial.

2

Pharmacokinetic and pharmacodynamic modeling of NN703, a growth hormone secretagogue, after a single po dose to human volunteers.

Agersø H, Ynddal L, Søgaard B, Zdravkovic M. Agersø H, et al. Among authors: ynddal l. J Clin Pharmacol. 2001 Feb;41(2):163-9. doi: 10.1177/00912700122009971. J Clin Pharmacol. 2001. PMID: 11210396 Clinical Trial.

3

The pharmacokinetics, pharmacodynamics, safety and tolerability of a single dose of NN703, a novel orally active growth hormone secretagogue in healthy male volunteers.

Zdravkovic M, Søgaard B, Ynddal L, Christiansen T, Agersø H, Thomsen MS, Falch JE, Ilondo MM. Zdravkovic M, et al. Among authors: ynddal l. Growth Horm IGF Res. 2000 Aug;10(4):193-8. doi: 10.1054/ghir.2000.0152. Growth Horm IGF Res. 2000. PMID: 11032702 Clinical Trial.

4

The pharmacokinetics, pharmacodynamics, safety and tolerability following 7 days daily oral treatment with NN703 in healthy male subjects.

Zdravkovic M, Christiansen T, Eliot L, Agersoe H, Thomsen MS, Falch JF, Søgaard B, Ynddal L, Ilondo MM. Zdravkovic M, et al. Among authors: ynddal l. Growth Horm IGF Res. 2001 Feb;11(1):41-8. doi: 10.1054/ghir.2000.0188. Growth Horm IGF Res. 2001. PMID: 11437473 Clinical Trial.

5

Human glucagon receptor antagonists with thiazole cores. A novel series with superior pharmacokinetic properties.

Madsen P, Kodra JT, Behrens C, Nishimura E, Jeppesen CB, Pridal L, Andersen B, Knudsen LB, Valcarce-Aspegren C, Guldbrandt M, Christensen IT, Jørgensen AS, Ynddal L, Brand CL, Bagger MA, Lau J. Madsen P, et al. Among authors: ynddal l. J Med Chem. 2009 May 14;52(9):2989-3000. doi: 10.1021/jm8016249. J Med Chem. 2009. PMID: 19385613

6

Pharmacokinetics and anti-hyperglycaemic efficacy of a novel inhibitor of glycogen phosphorylase, 1,4-dideoxy-1,4-imino-d- arabinitol, in glucagon-challenged rats and dogs and in diabetic ob/ob mice.

Mackay P, Ynddal L, Andersen JV, McCormack JG. Mackay P, et al. Among authors: ynddal l. Diabetes Obes Metab. 2003 Nov;5(6):397-407. doi: 10.1046/j.1463-1326.2003.00293.x. Diabetes Obes Metab. 2003. PMID: 14617225

7

Large dimeric ligands with favorable pharmacokinetic properties and peroxisome proliferator-activated receptor agonist activity in vitro and in vivo.

Sauerberg P, Bury PS, Mogensen JP, Deussen HJ, Pettersson I, Fleckner J, Nehlin J, Frederiksen KS, Albrektsen T, Din N, Svensson LA, Ynddal L, Wulff EM, Jeppesen L. Sauerberg P, et al. Among authors: ynddal l. J Med Chem. 2003 Nov 6;46(23):4883-94. doi: 10.1021/jm0309046. J Med Chem. 2003. PMID: 14584939

8

Identification and synthesis of a novel selective partial PPARdelta agonist with full efficacy on lipid metabolism in vitro and in vivo.

Sauerberg P, Olsen GS, Jeppesen L, Mogensen JP, Pettersson I, Jeppesen CB, Daugaard JR, Galsgaard ED, Ynddal L, Fleckner J, Panajotova V, Polivka Z, Pihera P, Havranek M, Wulff EM. Sauerberg P, et al. Among authors: ynddal l. J Med Chem. 2007 Apr 5;50(7):1495-503. doi: 10.1021/jm061202u. Epub 2007 Mar 8. J Med Chem. 2007. PMID: 17343371

9

Optimization of alkylidene hydrazide based human glucagon receptor antagonists. Discovery of the highly potent and orally available 3-cyano-4-hydroxybenzoic acid [1-(2,3,5,6-tetramethylbenzyl)-1H-indol-4-ylmethylene]hydrazide.

Madsen P, Ling A, Plewe M, Sams CK, Knudsen LB, Sidelmann UG, Ynddal L, Brand CL, Andersen B, Murphy D, Teng M, Truesdale L, Kiel D, May J, Kuki A, Shi S, Johnson MD, Teston KA, Feng J, Lakis J, Anderes K, Gregor V, Lau J. Madsen P, et al. Among authors: ynddal l. J Med Chem. 2002 Dec 19;45(26):5755-75. doi: 10.1021/jm0208572. J Med Chem. 2002. PMID: 12477359

10

Novel tricyclic-alpha-alkyloxyphenylpropionic acids: dual PPARalpha/gamma agonists with hypolipidemic and antidiabetic activity.

Sauerberg P, Pettersson I, Jeppesen L, Bury PS, Mogensen JP, Wassermann K, Brand CL, Sturis J, Wöldike HF, Fleckner J, Andersen AS, Mortensen SB, Svensson LA, Rasmussen HB, Lehmann SV, Polivka Z, Sindelar K, Panajotova V, Ynddal L, Wulff EM. Sauerberg P, et al. Among authors: ynddal l. J Med Chem. 2002 Feb 14;45(4):789-804. doi: 10.1021/jm010964g. J Med Chem. 2002. PMID: 11831892

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