Rosenquist A - Search Results

1

Compounds that activate the mouse melanocortin-1 receptor identified by screening a small molecule library based upon the beta-turn.

Haskell-Luevano C, Rosenquist A, Souers A, Khong KC, Ellman JA, Cone RD. Haskell-Luevano C, et al. Among authors: rosenquist a. J Med Chem. 1999 Oct 21;42(21):4380-7. doi: 10.1021/jm990190s. J Med Chem. 1999. PMID: 10543881

2

Optimization of a somatostatin mimetic via constrained amino acid and backbone incorporation.

Souers AJ, Rosenquist A, Jarvie EM, Ladlow M, Feniuk W, Ellman JA. Souers AJ, et al. Among authors: rosenquist a. Bioorg Med Chem Lett. 2000 Dec 18;10(24):2731-3. doi: 10.1016/s0960-894x(00)00552-7. Bioorg Med Chem Lett. 2000. PMID: 11133079

3

P2'-truncated BACE-1 inhibitors with a novel hydroxethylene-like core.

Meredith JA, Björklund C, Adolfsson H, Jansson K, Hallberg A, Rosenquist A, Samuelsson B. Meredith JA, et al. Among authors: rosenquist a. Eur J Med Chem. 2010 Feb;45(2):542-54. doi: 10.1016/j.ejmech.2009.10.041. Epub 2009 Nov 3. Eur J Med Chem. 2010. PMID: 19995674

4

Design and synthesis of potent inhibitors of plasmepsin I and II: X-ray crystal structure of inhibitor in complex with plasmepsin II.

Johansson PO, Lindberg J, Blackman MJ, Kvarnström I, Vrang L, Hamelink E, Hallberg A, Rosenquist A, Samuelsson B. Johansson PO, et al. Among authors: rosenquist a. J Med Chem. 2005 Jun 30;48(13):4400-9. doi: 10.1021/jm040884n. J Med Chem. 2005. PMID: 15974592

5

Synthesis, X-ray analysis, and biological evaluation of a new class of stereopure lactam-based HIV-1 protease inhibitors.

Wu X, Ohrngren P, Joshi AA, Trejos A, Persson M, Arvela RK, Wallberg H, Vrang L, Rosenquist A, Samuelsson BB, Unge J, Larhed M. Wu X, et al. Among authors: rosenquist a. J Med Chem. 2012 Mar 22;55(6):2724-36. doi: 10.1021/jm201620t. Epub 2012 Mar 13. J Med Chem. 2012. PMID: 22376008 Free PMC article.

6

3-Aryl pyridone derivatives. Potent and selective kappa opioid receptor agonists.

Semple G, Andersson BM, Chhajlani V, Georgsson J, Johansson M, Lindschoten M, Pontén F, Rosenquist A, Sörensen H, Swanson L, Swanson M. Semple G, et al. Among authors: rosenquist a. Bioorg Med Chem Lett. 2002 Jan 21;12(2):197-200. doi: 10.1016/s0960-894x(01)00691-6. Bioorg Med Chem Lett. 2002. PMID: 11755353

7

Design and synthesis of potent inhibitors of the malaria aspartyl proteases plasmepsin I and II. Use of solid-phase synthesis to explore novel statine motifs.

Johansson PO, Chen Y, Belfrage AK, Blackman MJ, Kvarnström I, Jansson K, Vrang L, Hamelink E, Hallberg A, Rosenquist A, Samuelsson B. Johansson PO, et al. Among authors: rosenquist a. J Med Chem. 2004 Jun 17;47(13):3353-66. doi: 10.1021/jm031106i. J Med Chem. 2004. PMID: 15189032

8

Design and synthesis of potent and selective BACE-1 inhibitors.

Björklund C, Oscarson S, Benkestock K, Borkakoti N, Jansson K, Lindberg J, Vrang L, Hallberg A, Rosenquist A, Samuelsson B. Björklund C, et al. Among authors: rosenquist a. J Med Chem. 2010 Feb 25;53(4):1458-64. doi: 10.1021/jm901168f. J Med Chem. 2010. PMID: 20128595

9

Synthesis of potent BACE-1 inhibitors incorporating a hydroxyethylene isostere as central core.

Wångsell F, Gustafsson K, Kvarnström I, Borkakoti N, Edlund M, Jansson K, Lindberg J, Hallberg A, Rosenquist A, Samuelsson B. Wångsell F, et al. Among authors: rosenquist a. Eur J Med Chem. 2010 Mar;45(3):870-82. doi: 10.1016/j.ejmech.2009.11.013. Epub 2009 Nov 12. Eur J Med Chem. 2010. PMID: 20036448

10

Solid-phase library synthesis of reversed-statine type inhibitors of the malarial aspartyl proteases plasmepsin I and II.

Dahlgren A, Kvarnström I, Vrang L, Hamelink E, Hallberg A, Rosenquist A, Samuelsson B. Dahlgren A, et al. Among authors: rosenquist a. Bioorg Med Chem. 2003 Mar 20;11(6):827-41. doi: 10.1016/s0968-0896(02)00568-0. Bioorg Med Chem. 2003. PMID: 12614868

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