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49 results

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Page 1
A novel ryanodine receptor 2 inhibitor, M201-A, enhances natriuresis, renal function and lusi-inotropic actions: Preclinical and phase I study.
Kaneko N, Loughrey CM, Smith G, Matsuda R, Hasunuma T, Mark PB, Toda M, Shinozaki M, Otani N, Kayley S, Da Silva Costa A, Martin TP, Dobi S, Saxena P, Shimamoto K, Ishikawa T, Kambayashi R, Riddell A, Elliott EB, McCarroll CS, Sakai T, Mitsuhisa Y, Hirano S, Kitai T, Kusano K, Inoue Y, Nakamura M, Kikuchi M, Toyoda S, Taguchi I, Fujiwara T, Sugiyama A, Kumagai Y, Iwata K. Kaneko N, et al. Among authors: loughrey cm. Br J Pharmacol. 2024 May 21. doi: 10.1111/bph.16379. Online ahead of print. Br J Pharmacol. 2024. PMID: 38773354
Ribonucleicacid interference or small molecule inhibition of Runx1 in the border zone prevents cardiac contractile dysfunction following myocardial infarction.
Martin TP, MacDonald EA, Bradley A, Watson H, Saxena P, Rog-Zielinska EA, Raheem A, Fisher S, Elbassioni AAM, Almuzaini O, Booth C, Campbell M, Riddell A, Herzyk P, Blyth K, Nixon C, Zentilin L, Berry C, Braun T, Giacca M, McBride MW, Nicklin SA, Cameron ER, Loughrey CM. Martin TP, et al. Among authors: loughrey cm. Cardiovasc Res. 2023 Dec 19;119(16):2663-2671. doi: 10.1093/cvr/cvad107. Cardiovasc Res. 2023. PMID: 37433039 Free PMC article.
Inhibition of myocardial cathepsin-L release during reperfusion following myocardial infarction improves cardiac function and reduces infarct size.
He W, McCarroll CS, Nather K, Ford K, Mangion K, Riddell A, O'Toole D, Zaeri A, Corcoran D, Carrick D, Lee MMY, McEntegart M, Davie A, Good R, Lindsay MM, Eteiba H, Rocchiccioli P, Watkins S, Hood S, Shaukat A, McArthur L, Elliott EB, McClure J, Hawksby C, Martin T, Petrie MC, Oldroyd KG, Smith GL; Oxford Acute Myocardial Infarction (OxAMI) Study; Channon KM, Berry C, Nicklin SA, Loughrey CM. He W, et al. Among authors: loughrey cm. Cardiovasc Res. 2022 May 6;118(6):1535-1547. doi: 10.1093/cvr/cvab204. Cardiovasc Res. 2022. PMID: 34132807 Free PMC article.
Preclinical models of myocardial infarction: from mechanism to translation.
Martin TP, MacDonald EA, Elbassioni AAM, O'Toole D, Zaeri AAI, Nicklin SA, Gray GA, Loughrey CM. Martin TP, et al. Among authors: loughrey cm. Br J Pharmacol. 2022 Mar;179(5):770-791. doi: 10.1111/bph.15595. Epub 2021 Aug 11. Br J Pharmacol. 2022. PMID: 34131903 Free article. Review.
Displacement Encoding With Stimulated Echoes Enables the Identification of Infarct Transmurality Early Postmyocardial Infarction.
Mangion K, Loughrey CM, Auger DA, McComb C, Lee MM, Corcoran D, McEntegart M, Davie A, Good R, Lindsay M, Eteiba H, Rocchiccioli P, Watkins S, Hood S, Shaukat A, Haig C, Epstein FH, Berry C. Mangion K, et al. Among authors: loughrey cm. J Magn Reson Imaging. 2020 Dec;52(6):1722-1731. doi: 10.1002/jmri.27295. Epub 2020 Jul 27. J Magn Reson Imaging. 2020. PMID: 32720405 Free article.
RUNX1: an emerging therapeutic target for cardiovascular disease.
Riddell A, McBride M, Braun T, Nicklin SA, Cameron E, Loughrey CM, Martin TP. Riddell A, et al. Among authors: loughrey cm. Cardiovasc Res. 2020 Jul 1;116(8):1410-1423. doi: 10.1093/cvr/cvaa034. Cardiovasc Res. 2020. PMID: 32154891 Free PMC article. Review.
What matters in Cardiovascular Research? Scientific discovery driving clinical delivery.
Guzik TJ, Antoniades C, Baker AH, Harrison DG, Loughrey CM, Maffia P, Murphy E, Nicklin SA, Peter K, Pearson J, Casadei B. Guzik TJ, et al. Among authors: loughrey cm. Cardiovasc Res. 2018 Oct 1;114(12):1565-1568. doi: 10.1093/cvr/cvy214. Cardiovasc Res. 2018. PMID: 30629152 Free PMC article. No abstract available.
49 results