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Secondary amides of (R)-3,3,3-trifluoro-2-hydroxy-2-methylpropionic acid as inhibitors of pyruvate dehydrogenase kinase.
Aicher TD, Anderson RC, Gao J, Shetty SS, Coppola GM, Stanton JL, Knorr DC, Sperbeck DM, Brand LJ, Vinluan CC, Kaplan EL, Dragland CJ, Tomaselli HC, Islam A, Lozito RJ, Liu X, Maniara WM, Fillers WS, DelGrande D, Walter RE, Mann WR. Aicher TD, et al. Among authors: fillers ws. J Med Chem. 2000 Jan 27;43(2):236-49. doi: 10.1021/jm990358+. J Med Chem. 2000. PMID: 10649979
Hypoglycemic prodrugs of 4-(2,2-dimethyl-1-oxopropyl)benzoic acid.
Aicher TD, Bebernitz GR, Bell PA, Brand LJ, Dain JG, Deems R, Fillers WS, Foley JE, Knorr DC, Nadelson J, Otero DA, Simpson R, Strohschein RJ, Young DA. Aicher TD, et al. Among authors: fillers ws. J Med Chem. 1999 Jan 14;42(1):153-63. doi: 10.1021/jm980438y. J Med Chem. 1999. PMID: 9888840
Oxygen sensors in vascular smooth muscle.
Katayama Y, Coburn RF, Fillers WS, Baron CB. Katayama Y, et al. Among authors: fillers ws. J Appl Physiol (1985). 1994 Nov;77(5):2086-92. doi: 10.1152/jappl.1994.77.5.2086. J Appl Physiol (1985). 1994. PMID: 7868420
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