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The hypersensitivity of the Chinese hamster ovary variant BL-10 to bleomycin killing is due to a lack of glutathione S-transferase-alpha activity.
Giaccia AJ, Lewis AD, Denko NC, Cholon A, Evans JW, Waldren CA, Stamato TD, Brown JM. Giaccia AJ, et al. Among authors: denko nc. Cancer Res. 1991 Aug 15;51(16):4463-9. Cancer Res. 1991. PMID: 1714344
As a means to understand the fundamental mechanisms of bleomycin cell killing, we previously isolated 19 bleomycin-sensitive mutants which represent at least six genetically distinct complementation groups (T.D. Stamato, B. Peters, P. Patil, N. Denko, R. Weinstein, …
As a means to understand the fundamental mechanisms of bleomycin cell killing, we previously isolated 19 bleomycin-sensitive mutants which r …
Cancer therapy and tumor physiology.
Giaccia AJ, Brown JM, Wouters B, Denko N, Koumenis C. Giaccia AJ, et al. Among authors: denko n. Science. 1998 Jan 2;279(5347):12-3. doi: 10.1126/science.279.5347.10e. Science. 1998. PMID: 9441397 No abstract available.
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