Reamer RA - Search Results

1

Phosphorylated morpholine acetal human neurokinin-1 receptor antagonists as water-soluble prodrugs.

Hale JJ, Mills SG, MacCoss M, Dorn CP, Finke PE, Budhu RJ, Reamer RA, Huskey SE, Luffer-Atlas D, Dean BJ, McGowan EM, Feeney WP, Chiu SH, Cascieri MA, Chicchi GG, Kurtz MM, Sadowski S, Ber E, Tattersall FD, Rupniak NM, Williams AR, Rycroft W, Hargreaves R, Metzger JM, MacIntyre DE. Hale JJ, et al. Among authors: reamer ra. J Med Chem. 2000 Mar 23;43(6):1234-41. doi: 10.1021/jm990617v. J Med Chem. 2000. PMID: 10737756

2

Discovery, total synthesis, HRV 3C-protease inhibitory activity, and structure-activity relationships of 2-methoxystypandrone and its analogues.

Singh SB, Graham PL, Reamer RA, Cordingley MG. Singh SB, et al. Among authors: reamer ra. Bioorg Med Chem Lett. 2001 Dec 17;11(24):3143-6. doi: 10.1016/s0960-894x(01)00648-5. Bioorg Med Chem Lett. 2001. PMID: 11720861

3

Efficient synthesis of NK(1) receptor antagonist aprepitant using a crystallization-induced diastereoselective transformation.

Brands KM, Payack JF, Rosen JD, Nelson TD, Candelario A, Huffman MA, Zhao MM, Li J, Craig B, Song ZJ, Tschaen DM, Hansen K, Devine PN, Pye PJ, Rossen K, Dormer PG, Reamer RA, Welch CJ, Mathre DJ, Tsou NN, McNamara JM, Reider PJ. Brands KM, et al. Among authors: reamer ra. J Am Chem Soc. 2003 Feb 26;125(8):2129-35. doi: 10.1021/ja027458g. J Am Chem Soc. 2003. PMID: 12590540

4

Stereocontrolled preparation of a nonpeptidal (-)-spirobicyclic NK-1 receptor antagonist.

Maligres PE, Waters MM, Lee J, Reamer RA, Askin D, Ashwood MS, Cameron M. Maligres PE, et al. Among authors: reamer ra. J Org Chem. 2002 Feb 22;67(4):1093-101. doi: 10.1021/jo0157472. J Org Chem. 2002. PMID: 11846649

5

Crystallization-induced diastereoselection: asymmetric synthesis of substance P inhibitors.

Pye PJ, Rossen K, Weissman SA, Maliakal A, Reamer RA, Ball R, Tsou NN, Volante RP, Reider PJ. Pye PJ, et al. Among authors: reamer ra. Chemistry. 2002 Mar 15;8(6):1372-6. doi: 10.1002/1521-3765(20020315)8:6<1372::aid-chem1372>3.0.co;2-6. Chemistry. 2002. PMID: 11921220

6

An efficient chemoenzymatic approach to (S)-gamma-fluoroleucine ethyl ester.

Limanto J, Shafiee A, Devine PN, Upadhyay V, Desmond RA, Foster BR, Gauthier DR Jr, Reamer RA, Volante RP. Limanto J, et al. Among authors: reamer ra. J Org Chem. 2005 Mar 18;70(6):2372-5. doi: 10.1021/jo047918j. J Org Chem. 2005. PMID: 15760235

7

Efficient one-pot synthesis of the 2-aminocarbonylpyrrolidin-4-ylthio-containing side chain of the new broad-spectrum carbapenem antibiotic ertapenem.

Brands KM, Jobson RB, Conrad KM, Williams JM, Pipik B, Cameron M, Davies AJ, Houghton PG, Ashwood MS, Cottrell IF, Reamer RA, Kennedy DJ, Dolling UH, Reider PJ. Brands KM, et al. Among authors: reamer ra. J Org Chem. 2002 Jul 12;67(14):4771-6. doi: 10.1021/jo011170c. J Org Chem. 2002. PMID: 12098287

8

Preparation of C-3,5-acyl furanoses via highly selective intramolecular acyl migration.

Xu F, Simmons B, Savary K, Yang C, Reamer RA. Xu F, et al. Among authors: reamer ra. J Org Chem. 2004 Oct 29;69(22):7783-6. doi: 10.1021/jo049121y. J Org Chem. 2004. PMID: 15498018

9

Chlorination/cyclodehydration of amino alcohols with SOCl2: an old reaction revisited.

Xu F, Simmons B, Reamer RA, Corley E, Murry J, Tschaen D. Xu F, et al. Among authors: reamer ra. J Org Chem. 2008 Jan 4;73(1):312-5. doi: 10.1021/jo701877h. Epub 2007 Dec 5. J Org Chem. 2008. PMID: 18052293

10

Synthesis of α-hydroxyacetophenones.

McLaughlin M, Belyk KM, Qian G, Reamer RA, Chen CY. McLaughlin M, et al. Among authors: reamer ra. J Org Chem. 2012 Jun 1;77(11):5144-8. doi: 10.1021/jo3005556. Epub 2012 May 22. J Org Chem. 2012. PMID: 22568765

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