Serpell LC - Search Results

1

Fiber diffraction of synthetic alpha-synuclein filaments shows amyloid-like cross-beta conformation.

Serpell LC, Berriman J, Jakes R, Goedert M, Crowther RA. Serpell LC, et al. Proc Natl Acad Sci U S A. 2000 Apr 25;97(9):4897-902. doi: 10.1073/pnas.97.9.4897. Proc Natl Acad Sci U S A. 2000. PMID: 10781096 Free PMC article.

2

Tau filaments from human brain and from in vitro assembly of recombinant protein show cross-beta structure.

Berriman J, Serpell LC, Oberg KA, Fink AL, Goedert M, Crowther RA. Berriman J, et al. Among authors: serpell lc. Proc Natl Acad Sci U S A. 2003 Jul 22;100(15):9034-8. doi: 10.1073/pnas.1530287100. Epub 2003 Jul 9. Proc Natl Acad Sci U S A. 2003. PMID: 12853572 Free PMC article.

3

Mutation E46K increases phospholipid binding and assembly into filaments of human alpha-synuclein.

Choi W, Zibaee S, Jakes R, Serpell LC, Davletov B, Crowther RA, Goedert M. Choi W, et al. Among authors: serpell lc. FEBS Lett. 2004 Oct 22;576(3):363-8. doi: 10.1016/j.febslet.2004.09.038. FEBS Lett. 2004. PMID: 15498564

4

Synuclein proteins of the pufferfish Fugu rubripes: sequences and functional characterization.

Yoshida H, Craxton M, Jakes R, Zibaee S, Tavaré R, Fraser G, Serpell LC, Davletov B, Crowther RA, Goedert M. Yoshida H, et al. Among authors: serpell lc. Biochemistry. 2006 Feb 28;45(8):2599-607. doi: 10.1021/bi051993m. Biochemistry. 2006. PMID: 16489753

5

Sequence Determinants for Amyloid Fibrillogenesis of Human alpha-Synuclein.

Zibaee S, Jakes R, Fraser G, Serpell LC, Crowther RA, Goedert M. Zibaee S, et al. Among authors: serpell lc. J Mol Biol. 2007 Nov 23;374(2):454-64. doi: 10.1016/j.jmb.2007.09.039. Epub 2007 Sep 20. J Mol Biol. 2007. PMID: 17936783

6

Human beta-synuclein rendered fibrillogenic by designed mutations.

Zibaee S, Fraser G, Jakes R, Owen D, Serpell LC, Crowther RA, Goedert M. Zibaee S, et al. Among authors: serpell lc. J Biol Chem. 2010 Dec 3;285(49):38555-67. doi: 10.1074/jbc.M110.160721. Epub 2010 Sep 10. J Biol Chem. 2010. PMID: 20833719 Free PMC article.

7

From genetics to pathology: tau and alpha-synuclein assemblies in neurodegenerative diseases.

Goedert M, Spillantini MG, Serpell LC, Berriman J, Smith MJ, Jakes R, Crowther RA. Goedert M, et al. Among authors: serpell lc. Philos Trans R Soc Lond B Biol Sci. 2001 Feb 28;356(1406):213-27. doi: 10.1098/rstb.2000.0767. Philos Trans R Soc Lond B Biol Sci. 2001. PMID: 11260802 Free PMC article. Review.

8

A simple algorithm locates beta-strands in the amyloid fibril core of alpha-synuclein, Abeta, and tau using the amino acid sequence alone.

Zibaee S, Makin OS, Goedert M, Serpell LC. Zibaee S, et al. Among authors: serpell lc. Protein Sci. 2007 May;16(5):906-18. doi: 10.1110/ps.062624507. Protein Sci. 2007. PMID: 17456743 Free PMC article.

9

Molecular basis for amyloid fibril formation and stability.

Makin OS, Atkins E, Sikorski P, Johansson J, Serpell LC. Makin OS, et al. Among authors: serpell lc. Proc Natl Acad Sci U S A. 2005 Jan 11;102(2):315-20. doi: 10.1073/pnas.0406847102. Epub 2005 Jan 3. Proc Natl Acad Sci U S A. 2005. PMID: 15630094 Free PMC article.

10

Proteasomal degradation of tau protein.

David DC, Layfield R, Serpell L, Narain Y, Goedert M, Spillantini MG. David DC, et al. J Neurochem. 2002 Oct;83(1):176-85. doi: 10.1046/j.1471-4159.2002.01137.x. J Neurochem. 2002. PMID: 12358741 Free article.

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