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Synthesis and SAR of benzyl and phenoxymethylene oxadiazole benzenesulfonamides as selective beta3 adrenergic receptor agonist antiobesity agents.
Biftu T, Feng DD, Liang GB, Kuo H, Qian X, Naylor EM, Colandrea VJ, Candelore MR, Cascieri MA, Colwell LF Jr, Forrest MJ, Hom GJ, MacIntyre DE, Stearns RA, Strader CD, Wyvratt MJ, Fisher MH, Weber AE. Biftu T, et al. Among authors: liang gb. Bioorg Med Chem Lett. 2000 Jul 3;10(13):1431-4. doi: 10.1016/s0960-894x(00)00268-7. Bioorg Med Chem Lett. 2000. PMID: 10888325
Synthesis and SAR of 2,3-diarylpyrrole inhibitors of parasite cGMP-dependent protein kinase as novel anticoccidial agents.
Biftu T, Feng D, Ponpipom M, Girotra N, Liang GB, Qian X, Bugianesi R, Simeone J, Chang L, Gurnett A, Liberator P, Dulski P, Leavitt PS, Crumley T, Misura A, Murphy T, Rattray S, Samaras S, Tamas T, Mathew J, Brown C, Thompson D, Schmatz D, Fisher M, Wyvratt M. Biftu T, et al. Among authors: liang gb. Bioorg Med Chem Lett. 2005 Jul 1;15(13):3296-301. doi: 10.1016/j.bmcl.2005.04.060. Bioorg Med Chem Lett. 2005. PMID: 15922595
Synthesis and SAR studies of very potent imidazopyridine antiprotozoal agents.
Biftu T, Feng D, Fisher M, Liang GB, Qian X, Scribner A, Dennis R, Lee S, Liberator PA, Brown C, Gurnett A, Leavitt PS, Thompson D, Mathew J, Misura A, Samaras S, Tamas T, Sina JF, McNulty KA, McKnight CG, Schmatz DM, Wyvratt M. Biftu T, et al. Among authors: liang gb. Bioorg Med Chem Lett. 2006 May 1;16(9):2479-83. doi: 10.1016/j.bmcl.2006.01.092. Epub 2006 Feb 7. Bioorg Med Chem Lett. 2006. PMID: 16464591
Synthesis and SAR studies of diarylpyrrole anticoccidial agents.
Qian X, Liang GB, Feng D, Fisher M, Crumley T, Rattray S, Dulski PM, Gurnett A, Leavitt PS, Liberator PA, Misura AS, Samaras S, Tamas T, Schmatz DM, Wyvratt M, Biftu T. Qian X, et al. Among authors: liang gb. Bioorg Med Chem Lett. 2006 May 15;16(10):2817-21. doi: 10.1016/j.bmcl.2006.01.041. Epub 2006 Mar 6. Bioorg Med Chem Lett. 2006. PMID: 16517161
Synthesis and SAR studies of potent imidazopyridine anticoccidial agents.
Liang GB, Qian X, Feng D, Fisher M, Brown CM, Gurnett A, Leavitt PS, Liberator PA, Misura AS, Tamas T, Schmatz DM, Wyvratt M, Biftu T. Liang GB, et al. Bioorg Med Chem Lett. 2007 Jul 1;17(13):3558-61. doi: 10.1016/j.bmcl.2007.04.041. Epub 2007 Apr 24. Bioorg Med Chem Lett. 2007. PMID: 17475489
Oxidiazole synthesis on solid supports.
Liang GB, Qian X. Liang GB, et al. Bioorg Med Chem Lett. 1999 Jul 19;9(14):2101-4. doi: 10.1016/s0960-894x(99)00343-1. Bioorg Med Chem Lett. 1999. PMID: 10450989
(3R)-4-[(3R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoyl]-3-(2,2,2-trifluoroethyl)-1,4-diazepan-2-one, a selective dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes.
Biftu T, Feng D, Qian X, Liang GB, Kieczykowski G, Eiermann G, He H, Leiting B, Lyons K, Petrov A, Sinha-Roy R, Zhang B, Scapin G, Patel S, Gao YD, Singh S, Wu J, Zhang X, Thornberry NA, Weber AE. Biftu T, et al. Among authors: liang gb. Bioorg Med Chem Lett. 2007 Jan 1;17(1):49-52. doi: 10.1016/j.bmcl.2006.09.099. Epub 2006 Oct 5. Bioorg Med Chem Lett. 2007. PMID: 17055272
66 results