Computational characterization of substrate binding and catalysis in S-adenosylhomocysteine hydrolase.
Hu Y, Yang X, Yin DH, Mahadevan J, Kuczera K, Schowen RL, Borchardt RT.
Hu Y, et al. Among authors: yang x.
Biochemistry. 2001 Dec 18;40(50):15143-52. doi: 10.1021/bi015690d.
Biochemistry. 2001.
PMID: 11735397
This enzyme exists in an open conformation (active site unoccupied) and a closed conformation (active site occupied with substrate or inhibitor) [Turner, M. A., Yang, X., Yin, D., Kuczera, K., Borchardt, R. T., and Howell, P. ...
This enzyme exists in an open conformation (active site unoccupied) and a closed conformation (active site occupied with substrate or inhibi …