Saavedra HI - Search Results

1

The RAS oncogene induces genomic instability in thyroid PCCL3 cells via the MAPK pathway.

Saavedra HI, Knauf JA, Shirokawa JM, Wang J, Ouyang B, Elisei R, Stambrook PJ, Fagin JA. Saavedra HI, et al. Oncogene. 2000 Aug 10;19(34):3948-54. doi: 10.1038/sj.onc.1203723. Oncogene. 2000. PMID: 10951588

2

MAPK mediates RAS-induced chromosome instability.

Saavedra HI, Fukasawa K, Conn CW, Stambrook PJ. Saavedra HI, et al. J Biol Chem. 1999 Dec 31;274(53):38083-90. doi: 10.1074/jbc.274.53.38083. J Biol Chem. 1999. PMID: 10608877 Free article.

3

Conditional apoptosis induced by oncogenic ras in thyroid cells.

Shirokawa JM, Elisei R, Knauf JA, Hara T, Wang J, Saavedra HI, Fagin JA. Shirokawa JM, et al. Among authors: saavedra hi. Mol Endocrinol. 2000 Nov;14(11):1725-38. doi: 10.1210/mend.14.11.0559. Mol Endocrinol. 2000. PMID: 11075808

4

Interleukin-3 increases the incidence of 5-azacytidine-induced thymic lymphomas in pBOR-Il-3 mice.

Saavedra HI, Wang TH, Hoyt PR, Popp D, Yang WK, Stambrook PJ. Saavedra HI, et al. Cell Immunol. 1996 Oct 10;173(1):116-23. doi: 10.1006/cimm.1996.0257. Cell Immunol. 1996. PMID: 8871607

5

Alloantigen gene therapy for squamous cell carcinoma of the head and neck: results of a phase-1 trial.

Gleich LL, Gluckman JL, Armstrong S, Biddinger PW, Miller MA, Balakrishnan K, Wilson KM, Saavedra HI, Stambrook PJ. Gleich LL, et al. Among authors: saavedra hi. Arch Otolaryngol Head Neck Surg. 1998 Oct;124(10):1097-104. doi: 10.1001/archotol.124.10.1097. Arch Otolaryngol Head Neck Surg. 1998. PMID: 9776187 Clinical Trial.

6

The Ras oncogene signals centrosome amplification in mammary epithelial cells through cyclin D1/Cdk4 and Nek2.

Zeng X, Shaikh FY, Harrison MK, Adon AM, Trimboli AJ, Carroll KA, Sharma N, Timmers C, Chodosh LA, Leone G, Saavedra HI. Zeng X, et al. Among authors: saavedra hi. Oncogene. 2010 Sep 9;29(36):5103-12. doi: 10.1038/onc.2010.253. Epub 2010 Jun 28. Oncogene. 2010. PMID: 20581865 Free PMC article.

7

Inactivation of E2F3 results in centrosome amplification.

Saavedra HI, Maiti B, Timmers C, Altura R, Tokuyama Y, Fukasawa K, Leone G. Saavedra HI, et al. Cancer Cell. 2003 Apr;3(4):333-46. doi: 10.1016/s1535-6108(03)00083-7. Cancer Cell. 2003. PMID: 12726860 Free PMC article.

8

Control of the p53-p21CIP1 Axis by E2f1, E2f2, and E2f3 is essential for G1/S progression and cellular transformation.

Sharma N, Timmers C, Trikha P, Saavedra HI, Obery A, Leone G. Sharma N, et al. Among authors: saavedra hi. J Biol Chem. 2006 Nov 24;281(47):36124-31. doi: 10.1074/jbc.M604152200. Epub 2006 Sep 27. J Biol Chem. 2006. PMID: 17008321 Free article.

9

E2f1, E2f2, and E2f3 control E2F target expression and cellular proliferation via a p53-dependent negative feedback loop.

Timmers C, Sharma N, Opavsky R, Maiti B, Wu L, Wu J, Orringer D, Trikha P, Saavedra HI, Leone G. Timmers C, et al. Among authors: saavedra hi. Mol Cell Biol. 2007 Jan;27(1):65-78. doi: 10.1128/MCB.02147-05. Mol Cell Biol. 2007. PMID: 17167174 Free PMC article.

10

The E2F1-3 transcription factors are essential for cellular proliferation.

Wu L, Timmers C, Maiti B, Saavedra HI, Sang L, Chong GT, Nuckolls F, Giangrande P, Wright FA, Field SJ, Greenberg ME, Orkin S, Nevins JR, Robinson ML, Leone G. Wu L, et al. Among authors: saavedra hi. Nature. 2001 Nov 22;414(6862):457-62. doi: 10.1038/35106593. Nature. 2001. PMID: 11719808

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