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Potent cyclic peptide inhibitors of VLA-4 (alpha4beta1 integrin)-mediated cell adhesion. Discovery of compounds like cyclo(MePhe-Leu-Asp-Val-D-Arg-D-Arg) (ZD7349) compatible with depot formulation.
J Pept Sci. 2000 Aug;6(8):398-412. doi: 10.1002/1099-1387(200008)6:8<398::AID-PSC270>3.0.CO;2-1.
J Pept Sci. 2000.
PMID: 10969869
Redirection of arachidonic acid metabolism by ICI D1542: effects on thrombus formation in the coronary artery of the anaesthetized dog.
McAuliffe SJ, Moors JA, Snow HM, Wayne M, Jessup R.
McAuliffe SJ, et al. Among authors: moors ja.
Br J Pharmacol. 1993 Apr;108(4):901-6. doi: 10.1111/j.1476-5381.1993.tb13484.x.
Br J Pharmacol. 1993.
PMID: 8485629
Free PMC article.
Item in Clipboard
The relationship between blood flow and diameter in the iliac artery of the anaesthetized dog: the role of endothelium-derived relaxing factor and shear stress.
Snow HM, McAuliffe SJ, Moors JA, Brownlie R.
Snow HM, et al. Among authors: moors ja.
Exp Physiol. 1994 Sep;79(5):635-45. doi: 10.1113/expphysiol.1994.sp003796.
Exp Physiol. 1994.
PMID: 7818856
Free article.
Item in Clipboard
The cardiovascular acitivity of ICI 118,587 a novel beta-adrenoceptor partial agonist [proceedings].
Barlow JJ, Main BD, Moors JA, Nuttall A, Snow HM.
Barlow JJ, et al. Among authors: moors ja.
Br J Pharmacol. 1979 Nov;67(3):412P.
Br J Pharmacol. 1979.
PMID: 40652
Free PMC article.
No abstract available.
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Detecting drug-induced prolongation of the QRS complex: new insights for cardiac safety assessment.
Cros C, Skinner M, Moors J, Lainee P, Valentin JP.
Cros C, et al.
Toxicol Appl Pharmacol. 2012 Dec 1;265(2):200-8. doi: 10.1016/j.taap.2012.10.007. Epub 2012 Oct 13.
Toxicol Appl Pharmacol. 2012.
PMID: 23073507
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Comparative effects of anti-platelet agents as adjuncts to tissue plasminogen activator in a dog model of occlusive coronary thrombosis.
McAuliffe SJ, Moors JA, Jones HB.
McAuliffe SJ, et al. Among authors: moors ja.
Br J Pharmacol. 1994 May;112(1):272-6. doi: 10.1111/j.1476-5381.1994.tb13063.x.
Br J Pharmacol. 1994.
PMID: 8032650
Free PMC article.
Item in Clipboard
A multi-site comparison of in vivo safety pharmacology studies conducted to support ICH S7A & B regulatory submissions.
Ewart L, Milne A, Adkins D, Benjamin A, Bialecki R, Chen Y, Ericsson AC, Gardner S, Grant C, Lengel D, Lindgren S, Lowing S, Marks L, Moors J, Oldman K, Pietras M, Prior H, Punton J, Redfern WS, Salmond R, Skinner M, Some M, Stanton A, Swedberg M, Finch J, Valentin JP.
Ewart L, et al.
J Pharmacol Toxicol Methods. 2013 Jul-Aug;68(1):30-43. doi: 10.1016/j.vascn.2013.04.008. Epub 2013 May 9.
J Pharmacol Toxicol Methods. 2013.
PMID: 23665080
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