Houslay MD - Search Results

1

Sub-family selective actions in the ability of Erk2 MAP kinase to phosphorylate and regulate the activity of PDE4 cyclic AMP-specific phosphodiesterases.

Baillie GS, MacKenzie SJ, McPhee I, Houslay MD. Baillie GS, et al. Among authors: houslay md. Br J Pharmacol. 2000 Oct;131(4):811-9. doi: 10.1038/sj.bjp.0703636. Br J Pharmacol. 2000. PMID: 11030732 Free PMC article.

2

Long PDE4 cAMP specific phosphodiesterases are activated by protein kinase A-mediated phosphorylation of a single serine residue in Upstream Conserved Region 1 (UCR1).

MacKenzie SJ, Baillie GS, McPhee I, MacKenzie C, Seamons R, McSorley T, Millen J, Beard MB, van Heeke G, Houslay MD. MacKenzie SJ, et al. Among authors: houslay md. Br J Pharmacol. 2002 Jun;136(3):421-33. doi: 10.1038/sj.bjp.0704743. Br J Pharmacol. 2002. PMID: 12023945 Free PMC article.

3

beta-Arrestin-mediated PDE4 cAMP phosphodiesterase recruitment regulates beta-adrenoceptor switching from Gs to Gi.

Baillie GS, Sood A, McPhee I, Gall I, Perry SJ, Lefkowitz RJ, Houslay MD. Baillie GS, et al. Among authors: houslay md. Proc Natl Acad Sci U S A. 2003 Feb 4;100(3):940-5. doi: 10.1073/pnas.262787199. Epub 2003 Jan 27. Proc Natl Acad Sci U S A. 2003. PMID: 12552097 Free PMC article. Retracted.

4

Remodelling of the PDE4 cAMP phosphodiesterase isoform profile upon monocyte-macrophage differentiation of human U937 cells.

Shepherd MC, Baillie GS, Stirling DI, Houslay MD. Shepherd MC, et al. Among authors: houslay md. Br J Pharmacol. 2004 May;142(2):339-51. doi: 10.1038/sj.bjp.0705770. Epub 2004 Apr 5. Br J Pharmacol. 2004. PMID: 15066910 Free PMC article.

5

Compartmentalisation of phosphodiesterases and protein kinase A: opposites attract.

Baillie GS, Scott JD, Houslay MD. Baillie GS, et al. Among authors: houslay md. FEBS Lett. 2005 Jun 13;579(15):3264-70. doi: 10.1016/j.febslet.2005.03.089. Epub 2005 Apr 14. FEBS Lett. 2005. PMID: 15943971 Free article. Review.

6

Investigation of extracellular signal-regulated kinase 2 mitogen-activated protein kinase phosphorylation and regulation of activity of PDE4 cyclic adenosine monophosphate-specific phosphodiesterases.

Hill EV, Houslay MD, Baillie GS. Hill EV, et al. Among authors: houslay md. Methods Mol Biol. 2005;307:225-37. doi: 10.1385/1-59259-839-0:225. Methods Mol Biol. 2005. PMID: 15988067

7

Chemical informatics uncovers a new role for moexipril as a novel inhibitor of cAMP phosphodiesterase-4 (PDE4).

Cameron RT, Coleman RG, Day JP, Yalla KC, Houslay MD, Adams DR, Shoichet BK, Baillie GS. Cameron RT, et al. Among authors: houslay md. Biochem Pharmacol. 2013 May 1;85(9):1297-305. doi: 10.1016/j.bcp.2013.02.026. Epub 2013 Mar 5. Biochem Pharmacol. 2013. PMID: 23473803 Free PMC article.

8

Intracellular compartmentalization of PDE4 cyclic AMP-specific phosphodiesterases.

Scotland G, Beard M, Erdogan S, Huston E, McCallum F, MacKenzie SJ, Peden AH, Pooley L, Rena NG, Ross AH, Yarwood SJ, Houslay MD. Scotland G, et al. Among authors: houslay md. Methods. 1998 Jan;14(1):65-79. doi: 10.1006/meth.1997.0566. Methods. 1998. PMID: 9500859

9

Stimulation of p70S6 kinase via a growth hormone-controlled phosphatidylinositol 3-kinase pathway leads to the activation of a PDE4A cyclic AMP-specific phosphodiesterase in 3T3-F442A preadipocytes.

MacKenzie SJ, Yarwood SJ, Peden AH, Bolger GB, Vernon RG, Houslay MD. MacKenzie SJ, et al. Among authors: houslay md. Proc Natl Acad Sci U S A. 1998 Mar 31;95(7):3549-54. doi: 10.1073/pnas.95.7.3549. Proc Natl Acad Sci U S A. 1998. PMID: 9520403 Free PMC article.

10

The MAP kinase ERK2 inhibits the cyclic AMP-specific phosphodiesterase HSPDE4D3 by phosphorylating it at Ser579.

Hoffmann R, Baillie GS, MacKenzie SJ, Yarwood SJ, Houslay MD. Hoffmann R, et al. Among authors: houslay md. EMBO J. 1999 Feb 15;18(4):893-903. doi: 10.1093/emboj/18.4.893. EMBO J. 1999. PMID: 10022832 Free PMC article.

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