Onstead L - Search Results

1

Reduction of Abeta accumulation in the Tg2576 animal model of Alzheimer's disease after oral administration of the phosphatidyl-inositol kinase inhibitor wortmannin.

Haugabook SJ, Le T, Yager D, Zenk B, Healy BM, Eckman EA, Prada C, Younkin L, Murphy P, Pinnix I, Onstead L, Sambamurti K, Golde TE, Dickson D, Younkin SG, Eckman CB. Haugabook SJ, et al. Among authors: onstead l. FASEB J. 2001 Jan;15(1):16-18. doi: 10.1096/fj.00-0528fje. Epub 2000 Nov 9. FASEB J. 2001. PMID: 11099491

2

Glycosylphosphatidylinositol-anchored proteins play an important role in the biogenesis of the Alzheimer's amyloid beta-protein.

Sambamurti K, Sevlever D, Koothan T, Refolo LM, Pinnix I, Gandhi S, Onstead L, Younkin L, Prada CM, Yager D, Ohyagi Y, Eckman CB, Rosenberry TL, Younkin SG. Sambamurti K, et al. Among authors: onstead l. J Biol Chem. 1999 Sep 17;274(38):26810-4. doi: 10.1074/jbc.274.38.26810. J Biol Chem. 1999. PMID: 10480887 Free article.

3

A novel gamma -secretase assay based on detection of the putative C-terminal fragment-gamma of amyloid beta protein precursor.

Pinnix I, Musunuru U, Tun H, Sridharan A, Golde T, Eckman C, Ziani-Cherif C, Onstead L, Sambamurti K. Pinnix I, et al. Among authors: onstead l. J Biol Chem. 2001 Jan 5;276(1):481-7. doi: 10.1074/jbc.M005968200. J Biol Chem. 2001. PMID: 11035007 Free article.

4

Abeta42 is essential for parenchymal and vascular amyloid deposition in mice.

McGowan E, Pickford F, Kim J, Onstead L, Eriksen J, Yu C, Skipper L, Murphy MP, Beard J, Das P, Jansen K, DeLucia M, Lin WL, Dolios G, Wang R, Eckman CB, Dickson DW, Hutton M, Hardy J, Golde T. McGowan E, et al. Among authors: onstead l. Neuron. 2005 Jul 21;47(2):191-199. doi: 10.1016/j.neuron.2005.06.030. Neuron. 2005. PMID: 16039562 Free PMC article.

5

Abeta40 inhibits amyloid deposition in vivo.

Kim J, Onstead L, Randle S, Price R, Smithson L, Zwizinski C, Dickson DW, Golde T, McGowan E. Kim J, et al. Among authors: onstead l. J Neurosci. 2007 Jan 17;27(3):627-33. doi: 10.1523/JNEUROSCI.4849-06.2007. J Neurosci. 2007. PMID: 17234594 Free PMC article.

6

Expression of BRI-amyloid beta peptide fusion proteins: a novel method for specific high-level expression of amyloid beta peptides.

Lewis PA, Piper S, Baker M, Onstead L, Murphy MP, Hardy J, Wang R, McGowan E, Golde TE. Lewis PA, et al. Among authors: onstead l. Biochim Biophys Acta. 2001 Jul 27;1537(1):58-62. doi: 10.1016/s0925-4439(01)00054-0. Biochim Biophys Acta. 2001. PMID: 11476963 Free article.

7

Characterization of recombinant, soluble beta-secretase from an insect cell expression system.

Mallender WD, Yager D, Onstead L, Nichols MR, Eckman C, Sambamurti K, Kopcho LM, Marcinkeviciene J, Copeland RA, Rosenberry TL. Mallender WD, et al. Among authors: onstead l. Mol Pharmacol. 2001 Mar;59(3):619-26. doi: 10.1124/mol.59.3.619. Mol Pharmacol. 2001. PMID: 11179458

8

Convertases other than furin cleave beta-secretase to its mature form.

Pinnix I, Council JE, Roseberry B, Onstead L, Mallender W, Sucic J, Sambamurti K. Pinnix I, et al. Among authors: onstead l. FASEB J. 2001 Aug;15(10):1810-2. doi: 10.1096/fj.00-0891fje. FASEB J. 2001. PMID: 11481238 Free article. No abstract available.

9

Expression of mBRI2 in mice.

Pickford F, Onstead L, Camacho-Prihar C, Hardy J, McGowan E. Pickford F, et al. Among authors: onstead l. Neurosci Lett. 2003 Feb 27;338(2):95-8. doi: 10.1016/s0304-3940(02)01356-3. Neurosci Lett. 2003. PMID: 12566161

10

Neurodegenerative diseases of Guam: analysis of TAU.

Pérez-Tur J, Buée L, Morris HR, Waring SC, Onstead L, Wavrant-De Vrièze F, Crook R, Buée-Scherrer V, Hof PR, Petersen RC, McGeer PL, Delacourte A, Hutton M, Siddique T, Ahlskog JE, Hardy J, Steele JC. Pérez-Tur J, et al. Among authors: onstead l. Neurology. 1999 Jul 22;53(2):411-3. doi: 10.1212/wnl.53.2.411. Neurology. 1999. PMID: 10430438

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