Jarvie EM - Search Results

1

Optimization of a somatostatin mimetic via constrained amino acid and backbone incorporation.

Souers AJ, Rosenquist A, Jarvie EM, Ladlow M, Feniuk W, Ellman JA. Souers AJ, et al. Among authors: jarvie em. Bioorg Med Chem Lett. 2000 Dec 18;10(24):2731-3. doi: 10.1016/s0960-894x(00)00552-7. Bioorg Med Chem Lett. 2000. PMID: 11133079

2

Selective somatostatin sst(2) receptor blockade with the novel cyclic octapeptide, CYN-154806.

Feniuk W, Jarvie E, Luo J, Humphrey PP. Feniuk W, et al. Neuropharmacology. 2000 Jun 8;39(8):1443-50. doi: 10.1016/s0028-3908(00)00035-6. Neuropharmacology. 2000. PMID: 10818260

3

Somatostatin sst2 receptor-mediated inhibition of parietal cell function in rat isolated gastric mucosa.

Wyatt MA, Jarvie E, Feniuk W, Humphrey PP. Wyatt MA, et al. Br J Pharmacol. 1996 Nov;119(5):905-10. doi: 10.1111/j.1476-5381.1996.tb15758.x. Br J Pharmacol. 1996. PMID: 8922739 Free PMC article.

4

Further evidence from functional studies for somatostatin receptor heterogeneity in guinea-pig isolated ileum, vas deferens and right atrium.

Feniuk W, Dimech J, Jarvie EM, Humphrey PP. Feniuk W, et al. Among authors: jarvie em. Br J Pharmacol. 1995 Jul;115(6):975-80. doi: 10.1111/j.1476-5381.1995.tb15906.x. Br J Pharmacol. 1995. PMID: 7582529 Free PMC article.

5

The solid phase synthesis of a series of tri-substituted hydantoin ligands for the somatostatin SST5 receptor.

Sciciński JJ, Barker MD, Murray PJ, Jarvie EM. Sciciński JJ, et al. Among authors: jarvie em. Bioorg Med Chem Lett. 1998 Dec 15;8(24):3609-14. doi: 10.1016/s0960-894x(98)00647-7. Bioorg Med Chem Lett. 1998. PMID: 9934480

6

Adenosine A(1) receptor-mediated inhibition of protein kinase A-induced calcitonin gene-related peptide release from rat trigeminal neurons.

Carruthers AM, Sellers LA, Jenkins DW, Jarvie EM, Feniuk W, Humphrey PP. Carruthers AM, et al. Among authors: jarvie em. Mol Pharmacol. 2001 Jun;59(6):1533-41. doi: 10.1124/mol.59.6.1533. Mol Pharmacol. 2001. PMID: 11353815

7

Molecular cloning and functional characterization of a rat somatostatin sst2(b) receptor splice variant.

Schindler M, Kidd EJ, Carruthers AM, Wyatt MA, Jarvie EM, Sellers LA, Feniuk W, Humphrey PP. Schindler M, et al. Among authors: jarvie em. Br J Pharmacol. 1998 Sep;125(1):209-17. doi: 10.1038/sj.bjp.0702064. Br J Pharmacol. 1998. PMID: 9776362 Free PMC article.

8

Identification of small molecule agonists of the motilin receptor.

Heightman TD, Conway E, Corbett DF, Macdonald GJ, Stemp G, Westaway SM, Celestini P, Gagliardi S, Riccaboni M, Ronzoni S, Vaidya K, Butler S, McKay F, Muir A, Powney B, Winborn K, Wise A, Jarvie EM, Sanger GJ. Heightman TD, et al. Among authors: jarvie em. Bioorg Med Chem Lett. 2008 Dec 15;18(24):6423-8. doi: 10.1016/j.bmcl.2008.10.071. Epub 2008 Oct 19. Bioorg Med Chem Lett. 2008. PMID: 18980843

9

The discovery of biaryl carboxamides as novel small molecule agonists of the motilin receptor.

Westaway SM, Brown SL, Conway E, Heightman TD, Johnson CN, Lapsley K, Macdonald GJ, MacPherson DT, Mitchell DJ, Myatt JW, Seal JT, Stanway SJ, Stemp G, Thompson M, Celestini P, Colombo A, Consonni A, Gagliardi S, Riccaboni M, Ronzoni S, Briggs MA, Matthews KL, Stevens AJ, Bolton VJ, Boyfield I, Jarvie EM, Stratton SC, Sanger GJ. Westaway SM, et al. Among authors: jarvie em. Bioorg Med Chem Lett. 2008 Dec 15;18(24):6429-36. doi: 10.1016/j.bmcl.2008.10.072. Epub 2008 Oct 19. Bioorg Med Chem Lett. 2008. PMID: 19006669

10

The discovery and optimisation of benzazepine sulfonamide and sulfones as potent agonists of the motilin receptor.

Bailey JM, Scott JS, Basilla JB, Bolton VJ, Boyfield I, Evans DG, Fleury E, Heightman TD, Jarvie EM, Lawless K, Matthews KL, McKay F, Mok H, Muir A, Orlek BS, Sanger GJ, Stemp G, Stevens AJ, Thompson M, Ward J, Vaidya K, Westaway SM. Bailey JM, et al. Among authors: jarvie em. Bioorg Med Chem Lett. 2009 Nov 15;19(22):6452-8. doi: 10.1016/j.bmcl.2009.09.027. Epub 2009 Sep 12. Bioorg Med Chem Lett. 2009. PMID: 19804969

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