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Discovery of a small molecule insulin mimetic with antidiabetic activity in mice.
Zhang B, Salituro G, Szalkowski D, Li Z, Zhang Y, Royo I, Vilella D, Díez MT, Pelaez F, Ruby C, Kendall RL, Mao X, Griffin P, Calaycay J, Zierath JR, Heck JV, Smith RG, Moller DE. Zhang B, et al. Among authors: pelaez f. Science. 1999 May 7;284(5416):974-7. doi: 10.1126/science.284.5416.974. Science. 1999. PMID: 10320380
Biodiversity, chemical diversity and drug discovery.
Singh SB, Pelaez F. Singh SB, et al. Among authors: pelaez f. Prog Drug Res. 2008;65:141, 143-74. doi: 10.1007/978-3-7643-8117-2_4. Prog Drug Res. 2008. PMID: 18084915 Review.
The discovery of enfumafungin, a novel antifungal compound produced by an endophytic Hormonema species biological activity and taxonomy of the producing organisms.
Peláez F, Cabello A, Platas G, Díez MT, González del Val A, Basilio A, Martán I, Vicente F, Bills GE, Giacobbe RA, Schwartz RE, Onish JC, Meinz MS, Abruzzo GK, Flattery AM, Kong L, Kurtz MB. Peláez F, et al. Syst Appl Microbiol. 2000 Oct;23(3):333-43. doi: 10.1016/s0723-2020(00)80062-4. Syst Appl Microbiol. 2000. PMID: 11108011
Discovery of FabH/FabF inhibitors from natural products.
Young K, Jayasuriya H, Ondeyka JG, Herath K, Zhang C, Kodali S, Galgoci A, Painter R, Brown-Driver V, Yamamoto R, Silver LL, Zheng Y, Ventura JI, Sigmund J, Ha S, Basilio A, Vicente F, Tormo JR, Pelaez F, Youngman P, Cully D, Barrett JF, Schmatz D, Singh SB, Wang J. Young K, et al. Among authors: pelaez f. Antimicrob Agents Chemother. 2006 Feb;50(2):519-26. doi: 10.1128/AAC.50.2.519-526.2006. Antimicrob Agents Chemother. 2006. PMID: 16436705 Free PMC article.
92 results