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Beta(3)-adrenoceptor agonist-induced increases in lipolysis, metabolic rate, facial flushing, and reflex tachycardia in anesthetized rhesus monkeys.
Hom GJ, Forrest MJ, Bach TJ, Brady E, Candelore MR, Cascieri MA, Fletcher DJ, Fisher MH, Iliff SA, Mathvink R, Metzger J, Pecore V, Saperstein R, Shih T, Weber AE, Wyvratt M, Zafian P, MacIntyre DE. Hom GJ, et al. Among authors: shih t. J Pharmacol Exp Ther. 2001 Apr;297(1):299-307. J Pharmacol Exp Ther. 2001. PMID: 11259557
Nodulisporic acid side-chain modifications: access to the 2", 3", 4", and 6" registers.
Chakravarty PK, Shih TL, Colletti SL, Ayer MB, Snedden C, Kuo H, Tyagarajan S, Gregory L, Zakson-Aiken M, Shoop WL, Schmatz DM, Wyvratt M, Fisher MH, Meinke PT. Chakravarty PK, et al. Among authors: shih tl. Bioorg Med Chem Lett. 2003 Jan 6;13(1):147-50. doi: 10.1016/s0960-894x(02)00826-0. Bioorg Med Chem Lett. 2003. PMID: 12467636
Discovery of the development candidate N-tert-butyl nodulisporamide: a safe and efficacious once monthly oral agent for the control of fleas and ticks on companion animals.
Meinke PT, Colletti SL, Fisher MH, Wyvratt MJ, Shih TL, Ayer MB, Li C, Lim J, Ok D, Salva S, Warmke LM, Zakson M, Michael BF, Demontigny P, Ostlind DA, Fink D, Drag M, Schmatz DM, Shoop WL. Meinke PT, et al. Among authors: shih tl. J Med Chem. 2009 Jun 11;52(11):3505-15. doi: 10.1021/jm801334v. J Med Chem. 2009. PMID: 19445514
Liquid chromatographic-tandem mass spectrometric urine assay for a highly metabolized cyclic ureidobenzenesulfonamide: issues concerning assay specificity and quality control preparation.
Fisher AL, DePuy E, Shih T, Stearns R, Lee Y, Gottesdiener K, Flattery S, De Smet M, Keymeulen B, Musson DG. Fisher AL, et al. Among authors: shih t. J Pharm Biomed Anal. 2001 Dec;26(5-6):739-52. doi: 10.1016/s0731-7085(01)00438-1. J Pharm Biomed Anal. 2001. PMID: 11600286
Rapid pharmacokinetic screening for the selection of new drug discovery candidates using a generic isocratic liquid chromatography--atmospheric pressure ionization tandem mass spectrometry method.
Colwell LF Jr, Tamvakopoulos CS, Wang PR, Pivnichny JV, Shih TL. Colwell LF Jr, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2002 May 25;772(1):89-98. doi: 10.1016/s1570-0232(02)00061-2. J Chromatogr B Analyt Technol Biomed Life Sci. 2002. PMID: 12016019
1,054 results