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Susceptibility genes for nicotine dependence: a genome scan and followup in an independent sample suggest that regions on chromosomes 2, 4, 10, 16, 17 and 18 merit further study.
Straub RE, Sullivan PF, Ma Y, Myakishev MV, Harris-Kerr C, Wormley B, Kadambi B, Sadek H, Silverman MA, Webb BT, Neale MC, Bulik CM, Joyce PR, Kendler KS. Straub RE, et al. Among authors: wormley b. Mol Psychiatry. 1999 Mar;4(2):129-44. doi: 10.1038/sj.mp.4000518. Mol Psychiatry. 1999. PMID: 10208445
No major schizophrenia locus detected on chromosome 1q in a large multicenter sample.
Levinson DF, Holmans PA, Laurent C, Riley B, Pulver AE, Gejman PV, Schwab SG, Williams NM, Owen MJ, Wildenauer DB, Sanders AR, Nestadt G, Mowry BJ, Wormley B, Bauché S, Soubigou S, Ribble R, Nertney DA, Liang KY, Martinolich L, Maier W, Norton N, Williams H, Albus M, Carpenter EB, DeMarchi N, Ewen-White KR, Walsh D, Jay M, Deleuze JF, O'Neill FA, Papadimitriou G, Weilbaecher A, Lerer B, O'Donovan MC, Dikeos D, Silverman JM, Kendler KS, Mallet J, Crowe RR, Walters M. Levinson DF, et al. Among authors: wormley b. Science. 2002 Apr 26;296(5568):739-41. doi: 10.1126/science.1069914. Science. 2002. PMID: 11976456
Genetic variation in the 6p22.3 gene DTNBP1, the human ortholog of the mouse dysbindin gene, is associated with schizophrenia.
Straub RE, Jiang Y, MacLean CJ, Ma Y, Webb BT, Myakishev MV, Harris-Kerr C, Wormley B, Sadek H, Kadambi B, Cesare AJ, Gibberman A, Wang X, O'Neill FA, Walsh D, Kendler KS. Straub RE, et al. Among authors: wormley b. Am J Hum Genet. 2002 Aug;71(2):337-48. doi: 10.1086/341750. Epub 2002 Jul 3. Am J Hum Genet. 2002. PMID: 12098102 Free PMC article.
Genome-wide scans of three independent sets of 90 Irish multiplex schizophrenia families and follow-up of selected regions in all families provides evidence for multiple susceptibility genes.
Straub RE, MacLean CJ, Ma Y, Webb BT, Myakishev MV, Harris-Kerr C, Wormley B, Sadek H, Kadambi B, O'Neill FA, Walsh D, Kendler KS. Straub RE, et al. Among authors: wormley b. Mol Psychiatry. 2002;7(6):542-59. doi: 10.1038/sj.mp.4001051. Mol Psychiatry. 2002. PMID: 12140777
Alcohol dependence is associated with the ZNF699 gene, a human locus related to Drosophila hangover, in the Irish Affected Sib Pair Study of Alcohol Dependence (IASPSAD) sample.
Riley BP, Kalsi G, Kuo PH, Vladimirov V, Thiselton DL, Vittum J, Wormley B, Grotewiel MS, Patterson DG, Sullivan PF, van den Oord E, Walsh D, Kendler KS, Prescott CA. Riley BP, et al. Among authors: wormley b. Mol Psychiatry. 2006 Nov;11(11):1025-31. doi: 10.1038/sj.mp.4001891. Epub 2006 Aug 29. Mol Psychiatry. 2006. PMID: 16940975
A region of 35 kb containing the trace amine associate receptor 6 (TAAR6) gene is associated with schizophrenia in the Irish study of high-density schizophrenia families.
Vladimirov V, Thiselton DL, Kuo PH, McClay J, Fanous A, Wormley B, Vittum J, Ribble R, Moher B, van den Oord E, O'Neill FA, Walsh D, Kendler KS, Riley BP. Vladimirov V, et al. Among authors: wormley b. Mol Psychiatry. 2007 Sep;12(9):842-53. doi: 10.1038/sj.mp.4001984. Epub 2007 May 15. Mol Psychiatry. 2007. PMID: 17505468
AKT1 is associated with schizophrenia across multiple symptom dimensions in the Irish study of high density schizophrenia families.
Thiselton DL, Vladimirov VI, Kuo PH, McClay J, Wormley B, Fanous A, O'Neill FA, Walsh D, Van den Oord EJ, Kendler KS, Riley BP. Thiselton DL, et al. Among authors: wormley b. Biol Psychiatry. 2008 Mar 1;63(5):449-57. doi: 10.1016/j.biopsych.2007.06.005. Epub 2007 Sep 6. Biol Psychiatry. 2008. PMID: 17825267 Free PMC article.
69 results