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Spiro(indoline-3,4'-piperidine) growth hormone secretagogues as ghrelin mimetics.
Palucki BL, Feighner SD, Pong S, McKee KK, Hreniuk DL, Tan C, Howard AD, Van der Ploeg LH, Patchett AA, Nargund RP. Palucki BL, et al. Among authors: patchett aa. Bioorg Med Chem Lett. 2001 Jul 23;11(14):1955-7. doi: 10.1016/s0960-894x(01)00324-9. Bioorg Med Chem Lett. 2001. PMID: 11459669
Melanocortin subtype 4 receptor agonists: structure-activity relationships about the 4-alkyl piperidine core.
Sebhat IK, Lai Y, Barakat K, Ye Z, Tang R, Kalyani RN, Vongs A, Macneil T, Weinberg DH, Cabello MA, Maroto M, Teran A, Fong TM, Van der Ploeg LH, Patchett AA, Nargund RP. Sebhat IK, et al. Among authors: patchett aa. Bioorg Med Chem Lett. 2007 Oct 15;17(20):5720-3. doi: 10.1016/j.bmcl.2006.11.084. Epub 2006 Dec 3. Bioorg Med Chem Lett. 2007. PMID: 17768046
Structural requirements for the activation of the human growth hormone secretagogue receptor by peptide and nonpeptide secretagogues.
Feighner SD, Howard AD, Prendergast K, Palyha OC, Hreniuk DL, Nargund R, Underwood D, Tata JR, Dean DC, Tan CP, McKee KK, Woods JW, Patchett AA, Smith RG, Van der Ploeg LH. Feighner SD, et al. Among authors: patchett aa. Mol Endocrinol. 1998 Jan;12(1):137-45. doi: 10.1210/mend.12.1.0051. Mol Endocrinol. 1998. PMID: 9440817
Tripeptide growth hormone secretagogues.
Yang L, Morriello G, Pan Y, Nargund RP, Barakat K, Prendergast K, Cheng K, Chan WW, Smith RG, Patchett AA. Yang L, et al. Among authors: patchett aa. Bioorg Med Chem Lett. 1998 Apr 7;8(7):759-64. doi: 10.1016/s0960-894x(98)00103-6. Bioorg Med Chem Lett. 1998. PMID: 9871537
A receptor in pituitary and hypothalamus that functions in growth hormone release.
Howard AD, Feighner SD, Cully DF, Arena JP, Liberator PA, Rosenblum CI, Hamelin M, Hreniuk DL, Palyha OC, Anderson J, Paress PS, Diaz C, Chou M, Liu KK, McKee KK, Pong SS, Chaung LY, Elbrecht A, Dashkevicz M, Heavens R, Rigby M, Sirinathsinghji DJ, Dean DC, Melillo DG, Patchett AA, Nargund R, Griffin PR, DeMartino JA, Gupta SK, Schaeffer JM, Smith RG, Van der Ploeg LH. Howard AD, et al. Among authors: patchett aa. Science. 1996 Aug 16;273(5277):974-7. doi: 10.1126/science.273.5277.974. Science. 1996. PMID: 8688086
117 results