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A genomewide scan for loci predisposing to type 2 diabetes in a U.K. population (the Diabetes UK Warren 2 Repository): analysis of 573 pedigrees provides independent replication of a susceptibility locus on chromosome 1q.
Wiltshire S, Hattersley AT, Hitman GA, Walker M, Levy JC, Sampson M, O'Rahilly S, Frayling TM, Bell JI, Lathrop GM, Bennett A, Dhillon R, Fletcher C, Groves CJ, Jones E, Prestwich P, Simecek N, Rao PV, Wishart M, Bottazzo GF, Foxon R, Howell S, Smedley D, Cardon LR, Menzel S, McCarthy MI. Wiltshire S, et al. Among authors: levy jc. Am J Hum Genet. 2001 Sep;69(3):553-69. doi: 10.1086/323249. Epub 2001 Aug 1. Am J Hum Genet. 2001. PMID: 11484155 Free PMC article.
Studies of association between the gene for calpain-10 and type 2 diabetes mellitus in the United Kingdom.
Evans JC, Frayling TM, Cassell PG, Saker PJ, Hitman GA, Walker M, Levy JC, O'Rahilly S, Rao PV, Bennett AJ, Jones EC, Menzel S, Prestwich P, Simecek N, Wishart M, Dhillon R, Fletcher C, Millward A, Demaine A, Wilkin T, Horikawa Y, Cox NJ, Bell GI, Ellard S, McCarthy MI, Hattersley AT. Evans JC, et al. Among authors: levy jc. Am J Hum Genet. 2001 Sep;69(3):544-52. doi: 10.1086/323315. Epub 2001 Jul 31. Am J Hum Genet. 2001. PMID: 11481585 Free PMC article.
Meta-analysis and a large association study confirm a role for calpain-10 variation in type 2 diabetes susceptibility.
Weedon MN, Schwarz PE, Horikawa Y, Iwasaki N, Illig T, Holle R, Rathmann W, Selisko T, Schulze J, Owen KR, Evans J, Del Bosque-Plata L, Hitman G, Walker M, Levy JC, Sampson M, Bell GI, McCarthy MI, Hattersley AT, Frayling TM. Weedon MN, et al. Among authors: levy jc. Am J Hum Genet. 2003 Nov;73(5):1208-12. doi: 10.1086/379285. Am J Hum Genet. 2003. PMID: 14574648 Free PMC article. No abstract available.
Analysis of parent-offspring trios provides evidence for linkage and association between the insulin gene and type 2 diabetes mediated exclusively through paternally transmitted class III variable number tandem repeat alleles.
Huxtable SJ, Saker PJ, Haddad L, Walker M, Frayling TM, Levy JC, Hitman GA, O'Rahilly S, Hattersley AT, McCarthy MI. Huxtable SJ, et al. Among authors: levy jc. Diabetes. 2000 Jan;49(1):126-30. doi: 10.2337/diabetes.49.1.126. Diabetes. 2000. PMID: 10615960
266 results