Owens TD - Search Results

1

Synthesis and crystal structure of a unique and homochiral N,S-bonded N,N'-bis(tert-butanesulfinyl)amidinate rhodium(I) complex.

Souers AJ, Owens TD, Oliver AG, Hollander FJ, Ellman JA. Souers AJ, et al. Among authors: owens td. Inorg Chem. 2001 Sep 24;40(20):5299-301. doi: 10.1021/ic0104205. Inorg Chem. 2001. PMID: 11559098 No abstract available.

2

N-tert-butanesulfinyl imines: versatile intermediates for the asymmetric synthesis of amines.

Ellman JA, Owens TD, Tang TP. Ellman JA, et al. Among authors: owens td. Acc Chem Res. 2002 Nov;35(11):984-95. doi: 10.1021/ar020066u. Acc Chem Res. 2002. PMID: 12437323

3

The preparation and utility of bis(sulfinyl)imidoamidine ligands for the copper-catalyzed Diels-Alder reaction.

Owens TD, Souers AJ, Ellman JA. Owens TD, et al. J Org Chem. 2003 Jan 10;68(1):3-10. doi: 10.1021/jo020524c. J Org Chem. 2003. PMID: 12515453

4

Atom-economical synthesis of the N(10)-C(17) fragment of cyclotheonamides via a novel Passerini reaction-deprotection-acyl migration strategy.

Owens TD, Semple JE. Owens TD, et al. Org Lett. 2001 Oct 18;3(21):3301-4. doi: 10.1021/ol0165239. Org Lett. 2001. PMID: 11594819

5

New synthetic technology for efficient construction of alpha-hydroxy-beta-amino amides via the Passerini reaction.

Semple JE, Owens TD, Nguyen K, Levy OE. Semple JE, et al. Among authors: owens td. Org Lett. 2000 Sep 7;2(18):2769-72. doi: 10.1021/ol0061485. Org Lett. 2000. PMID: 10964361

6

Novel, potent and selective chimeric FXa inhibitors featuring hydrophobic P1-ketoamide moieties.

Semple JE, Levy OE, Minami NK, Owens TD, Siev DV. Semple JE, et al. Among authors: owens td. Bioorg Med Chem Lett. 2000 Oct 16;10(20):2305-9. doi: 10.1016/s0960-894x(00)00458-3. Bioorg Med Chem Lett. 2000. PMID: 11055344

7

Design, synthesis, and evolution of a novel, selective, and orally bioavailable class of thrombin inhibitors: P1-argininal derivatives incorporating P3-P4 lactam sulfonamide moieties.

Semple JE, Rowley DC, Brunck TK, Ha-Uong T, Minami NK, Owens TD, Tamura SY, Goldman EA, Siev DV, Ardecky RJ, Carpenter SH, Ge Y, Richard BM, Nolan TG, Håkanson K, Tulinsky A, Nutt RF, Ripka WC. Semple JE, et al. Among authors: owens td. J Med Chem. 1996 Nov 8;39(23):4531-6. doi: 10.1021/jm960572n. J Med Chem. 1996. PMID: 8917639 No abstract available.

8

Potent and selective thrombin inhibitors featuring hydrophobic, basic P3-P4-aminoalkyllactam moieties.

Semple JE, Rowley DC, Owens TD, Minami NK, Uong TH, Brunck TK. Semple JE, et al. Among authors: owens td. Bioorg Med Chem Lett. 1998 Dec 15;8(24):3525-30. doi: 10.1016/s0960-894x(98)00636-2. Bioorg Med Chem Lett. 1998. PMID: 9934465

9

Alkoxide-catalyzed ring-opening of a novel homosaccharin derivative: synthesis of potent, selective P3-lactam thrombin inhibitors containing P4-o-alkoxycarbonylbenzylsulfonamide residues.

Owens TD, Semple JE. Owens TD, et al. Bioorg Med Chem Lett. 1998 Dec 15;8(24):3683-8. doi: 10.1016/s0960-894x(98)00667-2. Bioorg Med Chem Lett. 1998. PMID: 9934495

10

Structure-based drug design of RN486, a potent and selective Bruton's tyrosine kinase (BTK) inhibitor, for the treatment of rheumatoid arthritis.

Lou Y, Han X, Kuglstatter A, Kondru RK, Sweeney ZK, Soth M, McIntosh J, Litman R, Suh J, Kocer B, Davis D, Park J, Frauchiger S, Dewdney N, Zecic H, Taygerly JP, Sarma K, Hong J, Hill RJ, Gabriel T, Goldstein DM, Owens TD. Lou Y, et al. Among authors: owens td. J Med Chem. 2015 Jan 8;58(1):512-6. doi: 10.1021/jm500305p. Epub 2014 Apr 16. J Med Chem. 2015. PMID: 24712864

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

25 results

Search Page