Oral spray immunization may be an alternative to intranasal vaccine delivery to induce systemic antibodies but not nasal mucosal or cellular immunity.
Bakke H, Samdal HH, Holst J, Oftung F, Haugen IL, Kristoffersen AC, Haugan A, Janakova L, Korsvold GE, Krogh G, Andersen EA, Djupesland P, Holand T, Rappuoli R, Haneberg B.
Bakke H, et al. Among authors: samdal hh.
Scand J Immunol. 2006 Mar;63(3):223-31. doi: 10.1111/j.1365-3083.2006.01730.x.
Scand J Immunol. 2006.
PMID: 16499576
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