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Mechanistic studies on the reversible metabolism of rofecoxib to 5-hydroxyrofecoxib in the rat: evidence for transient ring opening of a substituted 2-furanone derivative using stable isotope-labeling techniques.
Baillie TA, Halpin RA, Matuszewski BK, Geer LA, Chavez-Eng CM, Dean D, Braun M, Doss G, Jones A, Marks T, Melillo D, Vyas KP. Baillie TA, et al. Among authors: matuszewski bk. Drug Metab Dispos. 2001 Dec;29(12):1614-28. Drug Metab Dispos. 2001. PMID: 11717181
High-performance liquid chromatographic-tandem mass spectrometric evaluation and determination of stable isotope labeled analogs of rofecoxib in human plasma samples from oral bioavailability studies.
Chavez-Eng CM, Constanzer ML, Matuszewski BK. Chavez-Eng CM, et al. Among authors: matuszewski bk. J Chromatogr B Analyt Technol Biomed Life Sci. 2002 Feb 5;767(1):117-29. doi: 10.1016/s0378-4347(01)00552-7. J Chromatogr B Analyt Technol Biomed Life Sci. 2002. PMID: 11863283
Development of high-performance liquid chromatography-tandem mass spectrometric methods for the determination of a new oxytocin receptor antagonist (L-368,899) extracted from human plasma and urine: a case of lack of specificity due to the presence of metabolites.
Matuszewski BK, Chavez-Eng CM, Constanzer ML. Matuszewski BK, et al. J Chromatogr B Biomed Sci Appl. 1998 Sep 25;716(1-2):195-208. doi: 10.1016/s0378-4347(98)00317-x. J Chromatogr B Biomed Sci Appl. 1998. PMID: 9824233
Determination of efavirenz, a selective non-nucleoside reverse transcriptase inhibitor, in human plasma using HPLC with post-column photochemical derivatization and fluorescence detection.
Matthews CZ, Woolf EJ, Mazenko RS, Haddix-Wiener H, Chavez-Eng CM, Constanzer ML, Doss GA, Matuszewski BK. Matthews CZ, et al. Among authors: matuszewski bk. J Pharm Biomed Anal. 2002 Jun 1;28(5):925-34. doi: 10.1016/s0731-7085(01)00709-9. J Pharm Biomed Anal. 2002. PMID: 12039635
87 results