Substrate binding stabilizes S-adenosylhomocysteine hydrolase in a closed conformation.
Yin D, Yang X, Hu Y, Kuczera K, Schowen RL, Borchardt RT, Squier TC.
Yin D, et al. Among authors: hu y.
Biochemistry. 2000 Aug 15;39(32):9811-8. doi: 10.1021/bi000595a.
Biochemistry. 2000.
PMID: 10933798
Comparison of crystal structures of S-adenosylhomocysteine (AdoHcy) hydrolase in the substrate-free, NAD(+) form [Hu, Y., Komoto, J., Huang, Y., Gomi, T., Ogawa, H., Takata, Y., Fujioka, M., and Takusagawa, F. (1999) Biochemistry 38, 8323-8333] and a s …
Comparison of crystal structures of S-adenosylhomocysteine (AdoHcy) hydrolase in the substrate-free, NAD(+) form [Hu, Y., Komo …