Alexander J - Search Results

1

Intestinal tumorigenesis in multiple intestinal neoplasia mice induced by the food mutagen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine: perinatal susceptibility, regional variation, and correlation with DNA adducts.

Steffensen IL, Schut HA, Paulsen JE, Andreassen A, Alexander J. Steffensen IL, et al. Among authors: alexander j. Cancer Res. 2001 Dec 15;61(24):8689-96. Cancer Res. 2001. PMID: 11751386

2

One dose of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) or 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) induces tumours in Min/+ mice by truncation mutations or LOH in the Apc gene.

Andreassen A, Møllersen L, Vikse R, Steffensen IL, Mikalsen A, Paulsen JE, Alexander J. Andreassen A, et al. Among authors: alexander j. Mutat Res. 2002 May 27;517(1-2):157-66. doi: 10.1016/s1383-5718(02)00065-7. Mutat Res. 2002. PMID: 12034317

3

The food mutagen 2-amino-9H-pyrido[2,3-b]indole (AalphaC) but not its methylated form (MeAalphaC) increases intestinal tumorigenesis in neonatally exposed multiple intestinal neoplasia mice.

Steffensen IL, Paulsen JE, Alexander J. Steffensen IL, et al. Among authors: alexander j. Carcinogenesis. 2002 Aug;23(8):1373-8. doi: 10.1093/carcin/23.8.1373. Carcinogenesis. 2002. PMID: 12151357

4

Age-dependent susceptibility to azoxymethane-induced and spontaneous tumorigenesis in the Min/+ mouse.

Paulsen JE, Steffensen IL, Namork E, Eide TJ, Alexander J. Paulsen JE, et al. Among authors: alexander j. Anticancer Res. 2003 Jan-Feb;23(1A):259-65. Anticancer Res. 2003. PMID: 12680222

5

Incorporation of the food mutagen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) into fur and correlation with intestinal tumourigenesis in Min/+ mice.

Steffensen IL, Janak K, Hegstad S, Andreassen A, Paulsen JE, Reistad R, Alexander J. Steffensen IL, et al. Among authors: alexander j. Pharmacol Toxicol. 2003 Mar;92(3):131-6. doi: 10.1034/j.1600-0773.2003.920305.x. Pharmacol Toxicol. 2003. PMID: 12753428

6

Adenomatous polyposis coli truncation mutations in 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-induced intestinal tumours of multiple intestinal neoplasia mice.

Møllersen L, Vikse R, Andreassen A, Steffensen IL, Mikalsen A, Paulsen JE, Alexander J. Møllersen L, et al. Among authors: alexander j. Mutat Res. 2004 Jan 10;557(1):29-40. doi: 10.1016/j.mrgentox.2003.09.008. Mutat Res. 2004. PMID: 14706516

7

Flat dysplastic aberrant crypt foci are related to tumorigenesis in the colon of azoxymethane-treated rat.

Paulsen JE, Løberg EM, Olstørn HB, Knutsen H, Steffensen IL, Alexander J. Paulsen JE, et al. Among authors: alexander j. Cancer Res. 2005 Jan 1;65(1):121-9. Cancer Res. 2005. PMID: 15665287

8

Age at exposure and Apc status influence the levels of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-DNA adducts in mouse intestine and liver.

Steffensen IL, Schut HA, Alexander J. Steffensen IL, et al. Among authors: alexander j. Mutat Res. 2005 Nov 10;587(1-2):73-89. doi: 10.1016/j.mrgentox.2005.07.004. Epub 2005 Oct 3. Mutat Res. 2005. PMID: 16202642

We have previously shown that C57BL/6J-Min/+ (multiple intestinal neoplasia) mice, heterozygous for the Min mutation in the adenomatous polyposis coli gene, were more susceptible to intestinal tumorigenesis and had higher intestinal PhIP-DNA adduct levels after exposure to the fo …

We have previously shown that C57BL/6J-Min/+ (multiple intestinal neoplasia) mice, heterozygous for the Min mutation in the adenomatous poly …

9

Impact of genetic background on spontaneous or 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-induced intestinal tumorigenesis in Min/+ mice.

Steffensen IL, Alexander J. Steffensen IL, et al. Among authors: alexander j. Cancer Lett. 2006 Aug 28;240(2):289-96. doi: 10.1016/j.canlet.2005.09.015. Epub 2005 Dec 15. Cancer Lett. 2006. PMID: 16343741

10

Role of nucleotide excision repair deficiency in intestinal tumorigenesis in multiple intestinal neoplasia (Min) mice.

Steffensen IL, Schut HA, Nesland JM, Tanaka K, Alexander J. Steffensen IL, et al. Among authors: alexander j. Mutat Res. 2006 Dec 10;611(1-2):71-82. doi: 10.1016/j.mrgentox.2006.07.004. Epub 2006 Sep 8. Mutat Res. 2006. PMID: 16962818

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