Mercer K - Search Results

1

Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras.

Jackson EL, Willis N, Mercer K, Bronson RT, Crowley D, Montoya R, Jacks T, Tuveson DA. Jackson EL, et al. Among authors: mercer k. Genes Dev. 2001 Dec 15;15(24):3243-8. doi: 10.1101/gad.943001. Genes Dev. 2001. PMID: 11751630 Free PMC article.

2

K-ras is an essential gene in the mouse with partial functional overlap with N-ras.

Johnson L, Greenbaum D, Cichowski K, Mercer K, Murphy E, Schmitt E, Bronson RT, Umanoff H, Edelmann W, Kucherlapati R, Jacks T. Johnson L, et al. Among authors: mercer k. Genes Dev. 1997 Oct 1;11(19):2468-81. doi: 10.1101/gad.11.19.2468. Genes Dev. 1997. PMID: 9334313 Free PMC article.

3

Mice heterozygous for a mutation at the Nf2 tumor suppressor locus develop a range of highly metastatic tumors.

McClatchey AI, Saotome I, Mercer K, Crowley D, Gusella JF, Bronson RT, Jacks T. McClatchey AI, et al. Among authors: mercer k. Genes Dev. 1998 Apr 15;12(8):1121-33. doi: 10.1101/gad.12.8.1121. Genes Dev. 1998. PMID: 9553042 Free PMC article.

4

Somatic activation of the K-ras oncogene causes early onset lung cancer in mice.

Johnson L, Mercer K, Greenbaum D, Bronson RT, Crowley D, Tuveson DA, Jacks T. Johnson L, et al. Among authors: mercer k. Nature. 2001 Apr 26;410(6832):1111-6. doi: 10.1038/35074129. Nature. 2001. PMID: 11323676

5

ARF mutation accelerates pituitary tumor development in Rb+/- mice.

Tsai KY, MacPherson D, Rubinson DA, Nikitin AY, Bronson R, Mercer KL, Crowley D, Jacks T. Tsai KY, et al. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16865-70. doi: 10.1073/pnas.262499599. Epub 2002 Dec 16. Proc Natl Acad Sci U S A. 2002. PMID: 12486224 Free PMC article.

6

Targeted deletion reveals an essential function for the telomere length regulator Trf1.

Karlseder J, Kachatrian L, Takai H, Mercer K, Hingorani S, Jacks T, de Lange T. Karlseder J, et al. Among authors: mercer k. Mol Cell Biol. 2003 Sep;23(18):6533-41. doi: 10.1128/MCB.23.18.6533-6541.2003. Mol Cell Biol. 2003. PMID: 12944479 Free PMC article.

7

Endogenous oncogenic K-ras(G12D) stimulates proliferation and widespread neoplastic and developmental defects.

Tuveson DA, Shaw AT, Willis NA, Silver DP, Jackson EL, Chang S, Mercer KL, Grochow R, Hock H, Crowley D, Hingorani SR, Zaks T, King C, Jacobetz MA, Wang L, Bronson RT, Orkin SH, DePinho RA, Jacks T. Tuveson DA, et al. Cancer Cell. 2004 Apr;5(4):375-87. doi: 10.1016/s1535-6108(04)00085-6. Cancer Cell. 2004. PMID: 15093544 Free article.

8

Impaired microRNA processing enhances cellular transformation and tumorigenesis.

Kumar MS, Lu J, Mercer KL, Golub TR, Jacks T. Kumar MS, et al. Nat Genet. 2007 May;39(5):673-7. doi: 10.1038/ng2003. Epub 2007 Apr 1. Nat Genet. 2007. PMID: 17401365

9

Modulation of tumor induction and progression of oncogenic K-ras-positive tumors in the presence of TGF- b1 haploinsufficiency.

Pandey J, Umphress SM, Kang Y, Angdisen J, Naumova A, Mercer KL, Jacks T, Jakowlew SB. Pandey J, et al. Carcinogenesis. 2007 Dec;28(12):2589-96. doi: 10.1093/carcin/bgm136. Epub 2007 Aug 8. Carcinogenesis. 2007. PMID: 17690114

10

p53 controls radiation-induced gastrointestinal syndrome in mice independent of apoptosis.

Kirsch DG, Santiago PM, di Tomaso E, Sullivan JM, Hou WS, Dayton T, Jeffords LB, Sodha P, Mercer KL, Cohen R, Takeuchi O, Korsmeyer SJ, Bronson RT, Kim CF, Haigis KM, Jain RK, Jacks T. Kirsch DG, et al. Among authors: mercer kl. Science. 2010 Jan 29;327(5965):593-6. doi: 10.1126/science.1166202. Epub 2009 Dec 17. Science. 2010. PMID: 20019247 Free PMC article.

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