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Expression of SV-40 T antigen in the small intestinal epithelium of transgenic mice results in proliferative changes in the crypt and reentry of villus-associated enterocytes into the cell cycle but has no apparent effect on cellular differentiation programs and does not cause neoplastic transformation.
Hauft SM, Kim SH, Schmidt GH, Pease S, Rees S, Harris S, Roth KA, Hansbrough JR, Cohn SM, Ahnen DJ, et al. Hauft SM, et al. Among authors: pease s. J Cell Biol. 1992 May;117(4):825-39. doi: 10.1083/jcb.117.4.825. J Cell Biol. 1992. PMID: 1349609 Free PMC article.
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