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Page 1
Increased insulin sensitivity despite lipodystrophy in Crebbp heterozygous mice.
Yamauchi T, Oike Y, Kamon J, Waki H, Komeda K, Tsuchida A, Date Y, Li MX, Miki H, Akanuma Y, Nagai R, Kimura S, Saheki T, Nakazato M, Naitoh T, Yamamura K, Kadowaki T. Yamauchi T, et al. Among authors: nagai r. Nat Genet. 2002 Feb;30(2):221-6. doi: 10.1038/ng829. Epub 2002 Jan 30. Nat Genet. 2002. PMID: 11818964
Globular adiponectin protected ob/ob mice from diabetes and ApoE-deficient mice from atherosclerosis.
Yamauchi T, Kamon J, Waki H, Imai Y, Shimozawa N, Hioki K, Uchida S, Ito Y, Takakuwa K, Matsui J, Takata M, Eto K, Terauchi Y, Komeda K, Tsunoda M, Murakami K, Ohnishi Y, Naitoh T, Yamamura K, Ueyama Y, Froguel P, Kimura S, Nagai R, Kadowaki T. Yamauchi T, et al. Among authors: nagai r. J Biol Chem. 2003 Jan 24;278(4):2461-8. doi: 10.1074/jbc.M209033200. Epub 2002 Nov 12. J Biol Chem. 2003. PMID: 12431986 Free article.
Cloning of adiponectin receptors that mediate antidiabetic metabolic effects.
Yamauchi T, Kamon J, Ito Y, Tsuchida A, Yokomizo T, Kita S, Sugiyama T, Miyagishi M, Hara K, Tsunoda M, Murakami K, Ohteki T, Uchida S, Takekawa S, Waki H, Tsuno NH, Shibata Y, Terauchi Y, Froguel P, Tobe K, Koyasu S, Taira K, Kitamura T, Shimizu T, Nagai R, Kadowaki T. Yamauchi T, et al. Among authors: nagai r. Nature. 2003 Jun 12;423(6941):762-9. doi: 10.1038/nature01705. Nature. 2003. PMID: 12802337
[The role of PPARgamma in the onset of type 2 diabetes].
Hara K, Yamauchi T, Kubota N, Tobe K, Yamazaki T, Nagai R, Kadowaki T. Hara K, et al. Among authors: nagai r. Nihon Yakurigaku Zasshi. 2003 Oct;122(4):317-24. doi: 10.1254/fpj.122.317. Nihon Yakurigaku Zasshi. 2003. PMID: 14501167 Review. Japanese.
Molecular mechanism of insulin resistance and obesity.
Kadowaki T, Hara K, Yamauchi T, Terauchi Y, Tobe K, Nagai R. Kadowaki T, et al. Among authors: nagai r. Exp Biol Med (Maywood). 2003 Nov;228(10):1111-7. doi: 10.1177/153537020322801003. Exp Biol Med (Maywood). 2003. PMID: 14610248 Review.
Both insulin signaling defects in the liver and obesity contribute to insulin resistance and cause diabetes in Irs2(-/-) mice.
Suzuki R, Tobe K, Aoyama M, Inoue A, Sakamoto K, Yamauchi T, Kamon J, Kubota N, Terauchi Y, Yoshimatsu H, Matsuhisa M, Nagasaka S, Ogata H, Tokuyama K, Nagai R, Kadowaki T. Suzuki R, et al. Among authors: nagai r. J Biol Chem. 2004 Jun 11;279(24):25039-49. doi: 10.1074/jbc.M311956200. Epub 2004 Mar 17. J Biol Chem. 2004. PMID: 15028732 Free article.
Role of uncoupling protein-2 up-regulation and triglyceride accumulation in impaired glucose-stimulated insulin secretion in a beta-cell lipotoxicity model overexpressing sterol regulatory element-binding protein-1c.
Yamashita T, Eto K, Okazaki Y, Yamashita S, Yamauchi T, Sekine N, Nagai R, Noda M, Kadowaki T. Yamashita T, et al. Among authors: nagai r. Endocrinology. 2004 Aug;145(8):3566-77. doi: 10.1210/en.2003-1602. Epub 2004 Apr 1. Endocrinology. 2004. PMID: 15059954
Insulin/Foxo1 pathway regulates expression levels of adiponectin receptors and adiponectin sensitivity.
Tsuchida A, Yamauchi T, Ito Y, Hada Y, Maki T, Takekawa S, Kamon J, Kobayashi M, Suzuki R, Hara K, Kubota N, Terauchi Y, Froguel P, Nakae J, Kasuga M, Accili D, Tobe K, Ueki K, Nagai R, Kadowaki T. Tsuchida A, et al. Among authors: nagai r. J Biol Chem. 2004 Jul 16;279(29):30817-22. doi: 10.1074/jbc.M402367200. Epub 2004 Apr 29. J Biol Chem. 2004. PMID: 15123605 Free article.
Targeted disruption of AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actions.
Yamauchi T, Nio Y, Maki T, Kobayashi M, Takazawa T, Iwabu M, Okada-Iwabu M, Kawamoto S, Kubota N, Kubota T, Ito Y, Kamon J, Tsuchida A, Kumagai K, Kozono H, Hada Y, Ogata H, Tokuyama K, Tsunoda M, Ide T, Murakami K, Awazawa M, Takamoto I, Froguel P, Hara K, Tobe K, Nagai R, Ueki K, Kadowaki T. Yamauchi T, et al. Among authors: nagai r. Nat Med. 2007 Mar;13(3):332-9. doi: 10.1038/nm1557. Epub 2007 Feb 1. Nat Med. 2007. PMID: 17268472
1,778 results