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Generation, validation and humanisation of a novel insulin resistant cell model.
Logie L, Ruiz-Alcaraz AJ, Schofield CJ, Hundal HS, Feuerstein GZ, Brady JD, Crowther D, Tommasi AM, Grierson CE, Shepherd B, Morris AD, Hansen MK, Pearson E, Sutherland C. Logie L, et al. Biochem Pharmacol. 2010 Oct 1;80(7):1042-9. doi: 10.1016/j.bcp.2010.06.011. Epub 2010 Jun 23. Biochem Pharmacol. 2010. PMID: 20599791
Cellular responses to the metal-binding properties of metformin.
Logie L, Harthill J, Patel K, Bacon S, Hamilton DL, Macrae K, McDougall G, Wang HH, Xue L, Jiang H, Sakamoto K, Prescott AR, Rena G. Logie L, et al. Diabetes. 2012 Jun;61(6):1423-33. doi: 10.2337/db11-0961. Epub 2012 Apr 9. Diabetes. 2012. PMID: 22492524 Free PMC article.
Mutation of the PDK1 PH domain inhibits protein kinase B/Akt, leading to small size and insulin resistance.
Bayascas JR, Wullschleger S, Sakamoto K, García-Martínez JM, Clacher C, Komander D, van Aalten DM, Boini KM, Lang F, Lipina C, Logie L, Sutherland C, Chudek JA, van Diepen JA, Voshol PJ, Lucocq JM, Alessi DR. Bayascas JR, et al. Among authors: logie l. Mol Cell Biol. 2008 May;28(10):3258-72. doi: 10.1128/MCB.02032-07. Epub 2008 Mar 17. Mol Cell Biol. 2008. PMID: 18347057 Free PMC article.
Investigation of salicylate hepatic responses in comparison with chemical analogues of the drug.
Cameron AR, Logie L, Patel K, Bacon S, Forteath C, Harthill J, Roberts A, Sutherland C, Stewart D, Viollet B, Sakamoto K, McDougall G, Foretz M, Rena G. Cameron AR, et al. Among authors: logie l. Biochim Biophys Acta. 2016 Aug;1862(8):1412-22. doi: 10.1016/j.bbadis.2016.04.015. Epub 2016 Apr 27. Biochim Biophys Acta. 2016. PMID: 27130437 Free PMC article.
44 results