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Modification of the pyridine moiety of non-peptidyl indole GnRH receptor antagonists.
Simeone JP, Bugianesi RL, Ponpipom MM, Yang YT, Lo JL, Yudkovitz JB, Cui J, Mount GR, Ren RN, Creighton M, Mao AH, Vincent SH, Cheng K, Goulet MT. Simeone JP, et al. Among authors: ren rn. Bioorg Med Chem Lett. 2002 Nov 18;12(22):3329-32. doi: 10.1016/s0960-894x(02)00751-5. Bioorg Med Chem Lett. 2002. PMID: 12392744
Orally bioavailable, indole-based nonpeptide GnRH receptor antagonists with high potency and functional activity.
Ashton WT, Sisco RM, Kieczykowski GR, Yang YT, Yudkovitz JB, Cui J, Mount GR, Ren RN, Wu TJ, Shen X, Lyons KA, Mao AH, Carlin JR, Karanam BV, Vincent SH, Cheng K, Goulet MT. Ashton WT, et al. Among authors: ren rn. Bioorg Med Chem Lett. 2001 Oct 8;11(19):2597-602. doi: 10.1016/s0960-894x(01)00512-1. Bioorg Med Chem Lett. 2001. PMID: 11551758
Both epilepsy and anti-seizure medications affect bone metabolism in children with self-limited epilepsy with centrotemporal spikes.
Shi XY, Ju J, Lu Q, Hu LY, Tian YP, Guo GH, Liu ZS, Wu GF, Zhu HM, Zhang YQ, Li D, Gao L, Yang L, Wang CY, Liao JX, Wang JW, Zhou SZ, Wang H, Li XJ, Gao JY, Zhang L, Shu XM, Li D, Li Y, Chen CH, Zhang XJ, Zhong JM, Zhai QX, Sun YH, Lin XF, Ren RN, Yin F, Chen YH, Jia FY, Yang ZX, Wang JL, Xia ZZ, Wang LW, Luo R, Zou LP. Shi XY, et al. Among authors: ren rn. Epilepsia. 2023 Oct;64(10):2667-2678. doi: 10.1111/epi.17733. Epub 2023 Aug 14. Epilepsia. 2023. PMID: 37522416
UNC13B variants associated with partial epilepsy with favourable outcome.
Wang J, Qiao JD, Liu XR, Liu DT, Chen YH, Wu Y, Sun Y, Yu J, Ren RN, Mei Z, Liu YX, Shi YW, Jiang M, Lin SM, He N, Li B, Bian WJ, Li BM, Yi YH, Su T, Liu HK, Gu WY, Liao WP. Wang J, et al. Among authors: ren rn. Brain. 2021 Nov 29;144(10):3050-3060. doi: 10.1093/brain/awab164. Brain. 2021. PMID: 33876820 Free PMC article.
16 results