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Global gene expression profiling of multiple myeloma, monoclonal gammopathy of undetermined significance, and normal bone marrow plasma cells.
Zhan F, Hardin J, Kordsmeier B, Bumm K, Zheng M, Tian E, Sanderson R, Yang Y, Wilson C, Zangari M, Anaissie E, Morris C, Muwalla F, van Rhee F, Fassas A, Crowley J, Tricot G, Barlogie B, Shaughnessy J Jr. Zhan F, et al. Among authors: yang y. Blood. 2002 Mar 1;99(5):1745-57. doi: 10.1182/blood.v99.5.1745. Blood. 2002. PMID: 11861292 Free article.
Heparanase promotes the spontaneous metastasis of myeloma cells to bone.
Yang Y, Macleod V, Bendre M, Huang Y, Theus AM, Miao HQ, Kussie P, Yaccoby S, Epstein J, Suva LJ, Kelly T, Sanderson RD. Yang Y, et al. Blood. 2005 Feb 1;105(3):1303-9. doi: 10.1182/blood-2004-06-2141. Epub 2004 Oct 7. Blood. 2005. PMID: 15471949 Free article.
The syndecan-1 heparan sulfate proteoglycan is a viable target for myeloma therapy.
Yang Y, MacLeod V, Dai Y, Khotskaya-Sample Y, Shriver Z, Venkataraman G, Sasisekharan R, Naggi A, Torri G, Casu B, Vlodavsky I, Suva LJ, Epstein J, Yaccoby S, Shaughnessy JD Jr, Barlogie B, Sanderson RD. Yang Y, et al. Blood. 2007 Sep 15;110(6):2041-8. doi: 10.1182/blood-2007-04-082495. Epub 2007 May 29. Blood. 2007. PMID: 17536013 Free PMC article.
Myeloma cell-derived Runx2 promotes myeloma progression in bone.
Trotter TN, Li M, Pan Q, Peker D, Rowan PD, Li J, Zhan F, Suva LJ, Javed A, Yang Y. Trotter TN, et al. Among authors: yang y. Blood. 2015 Jun 4;125(23):3598-608. doi: 10.1182/blood-2014-12-613968. Epub 2015 Apr 10. Blood. 2015. PMID: 25862559 Free PMC article.
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