Singaraja R - Search Results

1

ABCA1 regulatory variants influence coronary artery disease independent of effects on plasma lipid levels.

Zwarts KY, Clee SM, Zwinderman AH, Engert JC, Singaraja R, Loubser O, James E, Roomp K, Hudson TJ, Jukema JW, Kastelein JJ, Hayden MR. Zwarts KY, et al. Among authors: singaraja r. Clin Genet. 2002 Feb;61(2):115-25. doi: 10.1034/j.1399-0004.2002.610206.x. Clin Genet. 2002. PMID: 11940086

2

Increased ABCA1 activity protects against atherosclerosis.

Singaraja RR, Fievet C, Castro G, James ER, Hennuyer N, Clee SM, Bissada N, Choy JC, Fruchart JC, McManus BM, Staels B, Hayden MR. Singaraja RR, et al. J Clin Invest. 2002 Jul;110(1):35-42. doi: 10.1172/JCI15748. J Clin Invest. 2002. PMID: 12093886 Free PMC article.

3

Efflux and atherosclerosis: the clinical and biochemical impact of variations in the ABCA1 gene.

Singaraja RR, Brunham LR, Visscher H, Kastelein JJ, Hayden MR. Singaraja RR, et al. Arterioscler Thromb Vasc Biol. 2003 Aug 1;23(8):1322-32. doi: 10.1161/01.ATV.0000078520.89539.77. Epub 2003 May 22. Arterioscler Thromb Vasc Biol. 2003. PMID: 12763760 Review.

4

Accurate prediction of the functional significance of single nucleotide polymorphisms and mutations in the ABCA1 gene.

Brunham LR, Singaraja RR, Pape TD, Kejariwal A, Thomas PD, Hayden MR. Brunham LR, et al. Among authors: singaraja rr. PLoS Genet. 2005 Dec;1(6):e83. doi: 10.1371/journal.pgen.0010083. Epub 2005 Dec 30. PLoS Genet. 2005. PMID: 16429166 Free PMC article.

5

Variations on a gene: rare and common variants in ABCA1 and their impact on HDL cholesterol levels and atherosclerosis.

Brunham LR, Singaraja RR, Hayden MR. Brunham LR, et al. Among authors: singaraja rr. Annu Rev Nutr. 2006;26:105-29. doi: 10.1146/annurev.nutr.26.061505.111214. Annu Rev Nutr. 2006. PMID: 16704350 Review.

6

Truncation mutations in ABCA1 suppress normal upregulation of full-length ABCA1 by 9-cis-retinoic acid and 22-R-hydroxycholesterol.

Wellington CL, Yang YZ, Zhou S, Clee SM, Tan B, Hirano K, Zwarts K, Kwok A, Gelfer A, Marcil M, Newman S, Roomp K, Singaraja R, Collins J, Zhang LH, Groen AK, Hovingh K, Brownlie A, Tafuri S, Genest J Jr, Kastelein JJ, Hayden MR. Wellington CL, et al. Among authors: singaraja r. J Lipid Res. 2002 Nov;43(11):1939-49. doi: 10.1194/jlr.m200277-jlr200. J Lipid Res. 2002. PMID: 12401893 Free article.

7

Alterations of plasma lipids in mice via adenoviral-mediated hepatic overexpression of human ABCA1.

Wellington CL, Brunham LR, Zhou S, Singaraja RR, Visscher H, Gelfer A, Ross C, James E, Liu G, Huber MT, Yang YZ, Parks RJ, Groen A, Fruchart-Najib J, Hayden MR. Wellington CL, et al. Among authors: singaraja rr. J Lipid Res. 2003 Aug;44(8):1470-80. doi: 10.1194/jlr.M300110-JLR200. Epub 2003 May 1. J Lipid Res. 2003. PMID: 12730295 Free article.

8

Alternate transcripts expressed in response to diet reflect tissue-specific regulation of ABCA1.

Singaraja RR, James ER, Crim J, Visscher H, Chatterjee A, Hayden MR. Singaraja RR, et al. J Lipid Res. 2005 Oct;46(10):2061-71. doi: 10.1194/jlr.M500133-JLR200. Epub 2005 Jul 16. J Lipid Res. 2005. PMID: 16024915 Free article.

9

Specific mutations in ABCA1 have discrete effects on ABCA1 function and lipid phenotypes both in vivo and in vitro.

Singaraja RR, Visscher H, James ER, Chroni A, Coutinho JM, Brunham LR, Kang MH, Zannis VI, Chimini G, Hayden MR. Singaraja RR, et al. Circ Res. 2006 Aug 18;99(4):389-97. doi: 10.1161/01.RES.0000237920.70451.ad. Epub 2006 Jul 27. Circ Res. 2006. PMID: 16873719

10

Both hepatic and extrahepatic ABCA1 have discrete and essential functions in the maintenance of plasma high-density lipoprotein cholesterol levels in vivo.

Singaraja RR, Van Eck M, Bissada N, Zimetti F, Collins HL, Hildebrand RB, Hayden A, Brunham LR, Kang MH, Fruchart JC, Van Berkel TJ, Parks JS, Staels B, Rothblat GH, Fiévet C, Hayden MR. Singaraja RR, et al. Circulation. 2006 Sep 19;114(12):1301-9. doi: 10.1161/CIRCULATIONAHA.106.621433. Epub 2006 Aug 28. Circulation. 2006. PMID: 16940190

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