Tschesche H - Search Results

1

Modulation of the catalytic activity of neutrophil collagenase MMP-8 on bovine collagen I. Role of the activation cleavage and of the hemopexin-like domain.

Gioia M, Fasciglione GF, Marini S, D'Alessio S, De Sanctis G, Diekmann O, Pieper M, Politi V, Tschesche H, Coletta M. Gioia M, et al. Among authors: tschesche h. J Biol Chem. 2002 Jun 28;277(26):23123-30. doi: 10.1074/jbc.M110873200. Epub 2002 Apr 12. J Biol Chem. 2002. PMID: 11953425 Free article.

., Mookhtiar, K. A., Gao, Y., Brew, K., Dioszegi, M., Birkedal-Hansen, H., and van Wart, H. E. (1990) Biochemistry 29, 10628-10634; Knauper, V., Osthues, A., DeClerk, Y. A., Langley, K. A., Blaser, J., and Tschesche, H. (1993) Biochem. J. 291, 847-854; …

., Mookhtiar, K. A., Gao, Y., Brew, K., Dioszegi, M., Birkedal-Hansen, H., and van Wart, H. E. (1990) Biochemistry 29, 10628-1 …

2

Two crystal structures of human neutrophil collagenase, one complexed with a primed- and the other with an unprimed-side inhibitor: implications for drug design.

Gavuzzo E, Pochetti G, Mazza F, Gallina C, Gorini B, D'Alessio S, Pieper M, Tschesche H, Tucker PA. Gavuzzo E, et al. Among authors: tschesche h. J Med Chem. 2000 Sep 7;43(18):3377-85. doi: 10.1021/jm9909589. J Med Chem. 2000. PMID: 10978185

3

Computational study of the catalytic domain of human neutrophil collagenase. specific role of the S3 and S'3 subsites in the interaction with a phosphonate inhibitor.

Aschi M, Roccatano D, Di Nola A, Gallina C, Gavuzzo E, Pochetti G, Pieper M, Tschesche H, Mazza F. Aschi M, et al. Among authors: tschesche h. J Comput Aided Mol Des. 2002 Mar;16(3):213-25. doi: 10.1023/a:1020178822319. J Comput Aided Mol Des. 2002. PMID: 12363219

4

Degradation of kinins, angiotensins and substance P by polymorphonuclear matrix metalloproteinases MMP 8 and MMP 9.

Diekmann O, Tschesche H. Diekmann O, et al. Among authors: tschesche h. Braz J Med Biol Res. 1994 Aug;27(8):1865-76. Braz J Med Biol Res. 1994. PMID: 7538373

5

The N-terminus of collagenase MMP-8 determines superactivity and inhibition: a relation of structure and function analyzed by biomolecular interaction analysis.

Farr M, Pieper M, Calvete J, Tschesche H. Farr M, et al. Among authors: tschesche h. Biochemistry. 1999 Jun 1;38(22):7332-8. doi: 10.1021/bi982618f. Biochemistry. 1999. PMID: 10353844

6

1.8-A crystal structure of the catalytic domain of human neutrophil collagenase (matrix metalloproteinase-8) complexed with a peptidomimetic hydroxamate primed-side inhibitor with a distinct selectivity profile.

Betz M, Huxley P, Davies SJ, Mushtaq Y, Pieper M, Tschesche H, Bode W, Gomis-Rüth FX. Betz M, et al. Among authors: tschesche h. Eur J Biochem. 1997 Jul 1;247(1):356-63. doi: 10.1111/j.1432-1033.1997.00356.x. Eur J Biochem. 1997. PMID: 9249047 Free article.

7

Enhanced cleavage of type II collagen by collagenases in osteoarthritic articular cartilage.

Billinghurst RC, Dahlberg L, Ionescu M, Reiner A, Bourne R, Rorabeck C, Mitchell P, Hambor J, Diekmann O, Tschesche H, Chen J, Van Wart H, Poole AR. Billinghurst RC, et al. Among authors: tschesche h. J Clin Invest. 1997 Apr 1;99(7):1534-45. doi: 10.1172/JCI119316. J Clin Invest. 1997. PMID: 9119997 Free PMC article.

8

Expression, purification, characterization, and X-ray analysis of selenomethionine 215 variant of leukocyte collagenase.

Pieper M, Betz M, Budisa N, Gomis-Rüth FX, Bode W, Tschesche H. Pieper M, et al. Among authors: tschesche h. J Protein Chem. 1997 Aug;16(6):637-50. doi: 10.1023/a:1026327125333. J Protein Chem. 1997. PMID: 9263126

9

Structure determination and analysis of human neutrophil collagenase complexed with a hydroxamate inhibitor.

Grams F, Crimmin M, Hinnes L, Huxley P, Pieper M, Tschesche H, Bode W. Grams F, et al. Among authors: tschesche h. Biochemistry. 1995 Oct 31;34(43):14012-20. doi: 10.1021/bi00043a007. Biochemistry. 1995. PMID: 7577999

10

X-ray structures of human neutrophil collagenase complexed with peptide hydroxamate and peptide thiol inhibitors. Implications for substrate binding and rational drug design.

Grams F, Reinemer P, Powers JC, Kleine T, Pieper M, Tschesche H, Huber R, Bode W. Grams F, et al. Among authors: tschesche h. Eur J Biochem. 1995 Mar 15;228(3):830-41. doi: 10.1111/j.1432-1033.1995.tb20329.x. Eur J Biochem. 1995. PMID: 7737183 Free article.

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