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Ivermectin and nodulisporic acid receptors in Drosophila melanogaster contain both gamma-aminobutyric acid-gated Rdl and glutamate-gated GluCl alpha chloride channel subunits.
Ludmerer SW, Warren VA, Williams BS, Zheng Y, Hunt DC, Ayer MB, Wallace MA, Chaudhary AG, Egan MA, Meinke PT, Dean DC, Garcia ML, Cully DF, Smith MM. Ludmerer SW, et al. Among authors: cully df. Biochemistry. 2002 May 21;41(20):6548-60. doi: 10.1021/bi015920o. Biochemistry. 2002. PMID: 12009920
Drug-resistant Drosophila indicate glutamate-gated chloride channels are targets for the antiparasitics nodulisporic acid and ivermectin.
Kane NS, Hirschberg B, Qian S, Hunt D, Thomas B, Brochu R, Ludmerer SW, Zheng Y, Smith M, Arena JP, Cohen CJ, Schmatz D, Warmke J, Cully DF. Kane NS, et al. Among authors: cully df. Proc Natl Acad Sci U S A. 2000 Dec 5;97(25):13949-54. doi: 10.1073/pnas.240464697. Proc Natl Acad Sci U S A. 2000. PMID: 11095718 Free PMC article.
45 results