Valdez CA - Search Results

1

Sugar-modified conjugated diene analogues of adenosine and uridine: synthesis, interaction with S-adenosyl-L-homocysteine hydrolase, and antiviral and cytostatic effects.

Wnuk SF, Ro BO, Valdez CA, Lewandowska E, Valdez NX, Sacasa PR, Yin D, Zhang J, Borchardt RT, De Clercq E. Wnuk SF, et al. Among authors: valdez nx, valdez ca. J Med Chem. 2002 Jun 6;45(12):2651-8. doi: 10.1021/jm020064f. J Med Chem. 2002. PMID: 12036374

2

Doubly homologated dihalovinyl and acetylene analogues of adenosine: synthesis, interaction with S-adenosyl-L-homocysteine hydrolase, and antiviral and cytostatic effects.

Wnuk SF, Valdez CA, Khan J, Moutinho P, Robins MJ, Yang X, Borchardt RT, Balzarini J, De Clercq E. Wnuk SF, et al. Among authors: valdez ca. J Med Chem. 2000 Mar 23;43(6):1180-6. doi: 10.1021/jm990486y. J Med Chem. 2000. PMID: 10737751

3

Hydrolytic reactivity trends among potential prodrugs of the O2-glycosylated diazeniumdiolate family. Targeting nitric oxide to macrophages for antileishmanial activity.

Valdez CA, Saavedra JE, Showalter BM, Davies KM, Wilde TC, Citro ML, Barchi JJ Jr, Deschamps JR, Parrish D, El-Gayar S, Schleicher U, Bogdan C, Keefer LK. Valdez CA, et al. J Med Chem. 2008 Jul 10;51(13):3961-70. doi: 10.1021/jm8000482. Epub 2008 Jun 6. J Med Chem. 2008. PMID: 18533711 Free PMC article.

4

Synthesis and electrochemistry of 2-ethenyl and 2-ethanyl derivatives of 5-nitroimidazole and antimicrobial activity against Giardia lamblia.

Valdez CA, Tripp JC, Miyamoto Y, Kalisiak J, Hruz P, Andersen YS, Brown SE, Kangas K, Arzu LV, Davids BJ, Gillin FD, Upcroft JA, Upcroft P, Fokin VV, Smith DK, Sharpless KB, Eckmann L. Valdez CA, et al. J Med Chem. 2009 Jul 9;52(13):4038-53. doi: 10.1021/jm900356n. J Med Chem. 2009. PMID: 19480409 Free PMC article.

5

Diazeniumdiolate ions as leaving groups in anomeric displacement reactions: a protection-deprotection strategy for ionic diazeniumdiolates.

Showalter BM, Reynolds MM, Valdez CA, Saavedra JE, Davies KM, Klose JR, Chmurny GN, Citro ML, Barchi JJ Jr, Merz SI, Meyerhoff ME, Keefer LK. Showalter BM, et al. Among authors: valdez ca. J Am Chem Soc. 2005 Oct 19;127(41):14188-9. doi: 10.1021/ja054510a. J Am Chem Soc. 2005. PMID: 16218605

6

Tailored Synthesis of Nitric Oxide-Releasing Polyurethanes Using O-Protected Diazeniumdiolated Chain Extenders.

Reynolds MM, Saavedra JE, Showalter BM, Valdez CA, Shanklin AP, Oh BK, Keefer LK, Meyerhoff ME. Reynolds MM, et al. Among authors: valdez ca. J Mater Chem. 2010 Jan 1;20(15):3107-2114. doi: 10.1039/c000152j. J Mater Chem. 2010. PMID: 21132111 Free PMC article.

7

Predicting a Drug's Membrane Permeability: A Computational Model Validated With in Vitro Permeability Assay Data.

Bennion BJ, Be NA, McNerney MW, Lao V, Carlson EM, Valdez CA, Malfatti MA, Enright HA, Nguyen TH, Lightstone FC, Carpenter TS. Bennion BJ, et al. Among authors: valdez ca. J Phys Chem B. 2017 May 25;121(20):5228-5237. doi: 10.1021/acs.jpcb.7b02914. Epub 2017 May 12. J Phys Chem B. 2017. PMID: 28453293 Free article.

8

Unsaturated Sulfur Crown Ethers Can Extract Mercury(II) and Show Promise for Future Copernicium(II) Studies: A Combined Experimental and Computational Study.

Ferrier MG, Valdez CA, Singh SK, Hok S, Ray D, Gagliardi L, Despotopulos JD. Ferrier MG, et al. Among authors: valdez ca. Inorg Chem. 2022 Jan 17;61(2):807-817. doi: 10.1021/acs.inorgchem.1c01869. Epub 2021 Dec 29. Inorg Chem. 2022. PMID: 34965111

9

The biodistribution and pharmacokinetics of the oxime acetylcholinesterase reactivator RS194B in guinea pigs.

Malfatti MA, Enright HA, Be NA, Kuhn EA, Hok S, McNerney MW, Lao V, Nguyen TH, Lightstone FC, Carpenter TS, Bennion BJ, Valdez CA. Malfatti MA, et al. Among authors: valdez ca. Chem Biol Interact. 2017 Nov 1;277:159-167. doi: 10.1016/j.cbi.2017.09.016. Epub 2017 Sep 21. Chem Biol Interact. 2017. PMID: 28941624 Free PMC article.

10

Development of a CNS-permeable reactivator for nerve agent exposure: an iterative, multi-disciplinary approach.

Bennion BJ, Malfatti MA, Be NA, Enright HA, Hok S, Cadieux CL, Carpenter TS, Lao V, Kuhn EA, McNerney MW, Lightstone FC, Nguyen TH, Valdez CA. Bennion BJ, et al. Among authors: valdez ca. Sci Rep. 2021 Jul 30;11(1):15567. doi: 10.1038/s41598-021-94963-2. Sci Rep. 2021. PMID: 34330964 Free PMC article.

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