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Page 1
Synthesis and pharmacological characterization of a potent, orally active p38 kinase inhibitor.
Dumas J, Hatoum-Mokdad H, Sibley RN, Smith RA, Scott WJ, Khire U, Lee W, Wood J, Wolanin D, Cooley J, Bankston D, Redman AM, Schoenleber R, Caringal Y, Gunn D, Romero R, Osterhout M, Paulsen H, Housley TJ, Wilhelm SM, Pirro J, Chien DS, Ranges GE, Shrikhande A, Muzsi A, Bortolon E, Wakefield J, Gianpaolo Ostravage C, Bhargava A, Chau T. Dumas J, et al. Among authors: osterhout m. Bioorg Med Chem Lett. 2002 Jun 17;12(12):1559-62. doi: 10.1016/s0960-894x(02)00238-x. Bioorg Med Chem Lett. 2002. PMID: 12039561
p38 kinase inhibitors for the treatment of arthritis and osteoporosis: thienyl, furyl, and pyrrolyl ureas.
Redman AM, Johnson JS, Dally R, Swartz S, Wild H, Paulsen H, Caringal Y, Gunn D, Renick J, Osterhout M, Kingery-Wood J, Smith RA, Lee W, Dumas J, Wilhelm SM, Housley TJ, Bhargava A, Ranges GE, Shrikhande A, Young D, Bombara M, Scott WJ. Redman AM, et al. Among authors: osterhout m. Bioorg Med Chem Lett. 2001 Jan 8;11(1):9-12. doi: 10.1016/s0960-894x(00)00574-6. Bioorg Med Chem Lett. 2001. PMID: 11140741
Integration of optimized substituent patterns to produce highly potent 4-aryl-pyridine glucagon receptor antagonists.
Ladouceur GH, Cook JH, Hertzog DL, Jones JH, Hundertmark T, Korpusik M, Lease TG, Livingston JN, MacDougall ML, Osterhout MH, Phelan K, Romero RH, Schoen WR, Shao C, Smith RA. Ladouceur GH, et al. Among authors: osterhout mh. Bioorg Med Chem Lett. 2002 Dec 2;12(23):3421-4. doi: 10.1016/s0960-894x(02)00736-9. Bioorg Med Chem Lett. 2002. PMID: 12419375
Elucidating the pathways of degradation of denagliptin.
Joshi BK, Ramsey B, Johnson B, Patterson DE, Powers J, Facchine KL, Osterhout M, Leblanc MP, Bryant-Mills R, Copley RC, Sides SL. Joshi BK, et al. Among authors: osterhout m. J Pharm Sci. 2010 Jul;99(7):3030-40. doi: 10.1002/jps.22069. J Pharm Sci. 2010. PMID: 20112433
Results of the two incidence screenings in the National Lung Screening Trial.
Aberle DR, DeMello S, Berg CD, Black WC, Brewer B, Church TR, Clingan KL, Duan F, Fagerstrom RM, Gareen IF, Gatsonis CA, Gierada DS, Jain A, Jones GC, Mahon I, Marcus PM, Rathmell JM, Sicks J; National Lung Screening Trial Research Team. Aberle DR, et al. N Engl J Med. 2013 Sep 5;369(10):920-31. doi: 10.1056/NEJMoa1208962. N Engl J Med. 2013. PMID: 24004119 Free PMC article. Clinical Trial.
22 results