Hyperosmolarity and CD95L trigger CD95/EGF receptor association and tyrosine phosphorylation of CD95 as prerequisites for CD95 membrane trafficking and DISC formation.
Reinehr R, Schliess F, Häussinger D.
Reinehr R, et al.
FASEB J. 2003 Apr;17(6):731-3. doi: 10.1096/fj.02-0915fje. Epub 2003 Feb 5.
FASEB J. 2003.
PMID: 12586732
The mechanisms underlying CD95 ligand (CD95L)- and hyperosmolarity-induced activation of the CD95 system [Reinehr, R., Graf, D., Fischer, R., Schliess, F., and Haussinger, D. (2002) Hepatology 36, 602-614] as initial steps of apoptosis were studied. ...
The mechanisms underlying CD95 ligand (CD95L)- and hyperosmolarity-induced activation of the CD95 system [Reinehr, R., Graf, D …