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Page 1
Mutations truncating the EP300 acetylase in human cancers.
Gayther SA, Batley SJ, Linger L, Bannister A, Thorpe K, Chin SF, Daigo Y, Russell P, Wilson A, Sowter HM, Delhanty JD, Ponder BA, Kouzarides T, Caldas C. Gayther SA, et al. Among authors: kouzarides t. Nat Genet. 2000 Mar;24(3):300-3. doi: 10.1038/73536. Nat Genet. 2000. PMID: 10700188
Differential expression of selected histone modifier genes in human solid cancers.
Ozdağ H, Teschendorff AE, Ahmed AA, Hyland SJ, Blenkiron C, Bobrow L, Veerakumarasivam A, Burtt G, Subkhankulova T, Arends MJ, Collins VP, Bowtell D, Kouzarides T, Brenton JD, Caldas C. Ozdağ H, et al. Among authors: kouzarides t. BMC Genomics. 2006 Apr 25;7:90. doi: 10.1186/1471-2164-7-90. BMC Genomics. 2006. PMID: 16638127 Free PMC article.
p300 is required for orderly G1/S transition in human cancer cells.
Iyer NG, Xian J, Chin SF, Bannister AJ, Daigo Y, Aparicio S, Kouzarides T, Caldas C. Iyer NG, et al. Among authors: kouzarides t. Oncogene. 2007 Jan 4;26(1):21-9. doi: 10.1038/sj.onc.1209771. Epub 2006 Jul 31. Oncogene. 2007. PMID: 16878158
EMSY links the BRCA2 pathway to sporadic breast and ovarian cancer.
Hughes-Davies L, Huntsman D, Ruas M, Fuks F, Bye J, Chin SF, Milner J, Brown LA, Hsu F, Gilks B, Nielsen T, Schulzer M, Chia S, Ragaz J, Cahn A, Linger L, Ozdag H, Cattaneo E, Jordanova ES, Schuuring E, Yu DS, Venkitaraman A, Ponder B, Doherty A, Aparicio S, Bentley D, Theillet C, Ponting CP, Caldas C, Kouzarides T. Hughes-Davies L, et al. Among authors: kouzarides t. Cell. 2003 Nov 26;115(5):523-35. doi: 10.1016/s0092-8674(03)00930-9. Cell. 2003. PMID: 14651845 Free article.
Isothiazolones as inhibitors of PCAF and p300 histone acetyltransferase activity.
Stimson L, Rowlands MG, Newbatt YM, Smith NF, Raynaud FI, Rogers P, Bavetsias V, Gorsuch S, Jarman M, Bannister A, Kouzarides T, McDonald E, Workman P, Aherne GW. Stimson L, et al. Among authors: kouzarides t. Mol Cancer Ther. 2005 Oct;4(10):1521-32. doi: 10.1158/1535-7163.MCT-05-0135. Mol Cancer Ther. 2005. PMID: 16227401
Generation of a Selective Small Molecule Inhibitor of the CBP/p300 Bromodomain for Leukemia Therapy.
Picaud S, Fedorov O, Thanasopoulou A, Leonards K, Jones K, Meier J, Olzscha H, Monteiro O, Martin S, Philpott M, Tumber A, Filippakopoulos P, Yapp C, Wells C, Che KH, Bannister A, Robson S, Kumar U, Parr N, Lee K, Lugo D, Jeffrey P, Taylor S, Vecellio ML, Bountra C, Brennan PE, O'Mahony A, Velichko S, Müller S, Hay D, Daniels DL, Urh M, La Thangue NB, Kouzarides T, Prinjha R, Schwaller J, Knapp S. Picaud S, et al. Among authors: kouzarides t. Cancer Res. 2015 Dec 1;75(23):5106-5119. doi: 10.1158/0008-5472.CAN-15-0236. Epub 2015 Nov 9. Cancer Res. 2015. PMID: 26552700 Free PMC article.
The acetyltransferase activity of CBP stimulates transcription.
Martinez-Balbás MA, Bannister AJ, Martin K, Haus-Seuffert P, Meisterernst M, Kouzarides T. Martinez-Balbás MA, et al. Among authors: kouzarides t. EMBO J. 1998 May 15;17(10):2886-93. doi: 10.1093/emboj/17.10.2886. EMBO J. 1998. PMID: 9582282 Free PMC article.
The cell cycle-regulating transcription factors E2F-RB.
Brehm A, Miska E, Reid J, Bannister A, Kouzarides T. Brehm A, et al. Among authors: kouzarides t. Br J Cancer. 1999 Jul;80 Suppl 1:38-41. Br J Cancer. 1999. PMID: 10466760 Review. No abstract available.
200 results