Chaudhary AG - Search Results

1

A novel P450-catalyzed transformation of the 2,2,6,6-tetramethyl piperidine moiety to a 2,2-dimethyl pyrrolidine in human liver microsomes: characterization by high resolution quadrupole-time-of-flight mass spectrometry and 1H-NMR.

Yin W, Doss GA, Stearns RA, Chaudhary AG, Hop CE, Franklin RB, Kumar S. Yin W, et al. Among authors: chaudhary ag. Drug Metab Dispos. 2003 Feb;31(2):215-23. doi: 10.1124/dmd.31.2.215. Drug Metab Dispos. 2003. PMID: 12527703

2

Addressing the metabolic activation potential of new leads in drug discovery: a case study using ion trap mass spectrometry and tritium labeling techniques.

Samuel K, Yin W, Stearns RA, Tang YS, Chaudhary AG, Jewell JP, Lanza T Jr, Lin LS, Hagmann WK, Evans DC, Kumar S. Samuel K, et al. Among authors: chaudhary ag. J Mass Spectrom. 2003 Feb;38(2):211-21. doi: 10.1002/jms.434. J Mass Spectrom. 2003. PMID: 12577288

3

Development and validation of a high-throughput radiometric cyp2c9 inhibition assay using tritiated diclofenac.

Di Marco A, Marcucci I, Chaudhary A, Taliani M, Laufer R. Di Marco A, et al. Drug Metab Dispos. 2005 Mar;33(3):359-64. doi: 10.1124/dmd.104.002915. Epub 2004 Dec 17. Drug Metab Dispos. 2005. PMID: 15608129

4

Development and validation of a high-throughput radiometric CYP3A4/5 inhibition assay using tritiated testosterone.

Di Marco A, Marcucci I, Verdirame M, Pérez J, Sanchez M, Peláez F, Chaudhary A, Laufer R. Di Marco A, et al. Drug Metab Dispos. 2005 Mar;33(3):349-58. doi: 10.1124/dmd.104.002873. Epub 2004 Dec 17. Drug Metab Dispos. 2005. PMID: 15608130

5

High-throughput radiometric CYP2C19 inhibition assay using tritiated (S)-mephenytoin.

Di Marco A, Cellucci A, Chaudhary A, Fonsi M, Laufer R. Di Marco A, et al. Drug Metab Dispos. 2007 Oct;35(10):1737-43. doi: 10.1124/dmd.107.016345. Epub 2007 Jun 28. Drug Metab Dispos. 2007. PMID: 17600081

6

Fluoroolefins as amide bond mimics in dipeptidyl peptidase IV inhibitors.

Edmondson SD, Wei L, Xu J, Shang J, Xu S, Pang J, Chaudhary A, Dean DC, He H, Leiting B, Lyons KA, Patel RA, Patel SB, Scapin G, Wu JK, Beconi MG, Thornberry NA, Weber AE. Edmondson SD, et al. Bioorg Med Chem Lett. 2008 Apr 1;18(7):2409-13. doi: 10.1016/j.bmcl.2008.02.050. Epub 2008 Feb 26. Bioorg Med Chem Lett. 2008. PMID: 18331795

7

Ivermectin and nodulisporic acid receptors in Drosophila melanogaster contain both gamma-aminobutyric acid-gated Rdl and glutamate-gated GluCl alpha chloride channel subunits.

Ludmerer SW, Warren VA, Williams BS, Zheng Y, Hunt DC, Ayer MB, Wallace MA, Chaudhary AG, Egan MA, Meinke PT, Dean DC, Garcia ML, Cully DF, Smith MM. Ludmerer SW, et al. Among authors: chaudhary ag. Biochemistry. 2002 May 21;41(20):6548-60. doi: 10.1021/bi015920o. Biochemistry. 2002. PMID: 12009920

8

Pharmacology and expression analysis of glycine transporter GlyT1 with [3H]-(N-[3-(4'-fluorophenyl)-3-(4'phenylphenoxy)propyl])sarcosine.

Mallorga PJ, Williams JB, Jacobson M, Marques R, Chaudhary A, Conn PJ, Pettibone DJ, Sur C. Mallorga PJ, et al. Neuropharmacology. 2003 Oct;45(5):585-93. doi: 10.1016/s0028-3908(03)00227-2. Neuropharmacology. 2003. PMID: 12941372

9

A nonpeptide oxytocin receptor antagonist radioligand highly selective for human receptors.

Lemaire W, O'Brien JA, Burno M, Chaudhary AG, Dean DC, Williams PD, Freidinger RM, Pettibone DJ, Williams DL Jr. Lemaire W, et al. Among authors: chaudhary ag. Eur J Pharmacol. 2002 Aug 16;450(1):19-28. doi: 10.1016/s0014-2999(02)02048-4. Eur J Pharmacol. 2002. PMID: 12176104

10

Screening cascade and development of potential Positron Emission Tomography radiotracers for mGluR5: in vitro and in vivo characterization.

Patel S, Ndubizu O, Hamill T, Chaudhary A, Burns HD, Hargreaves R, Gibson RE. Patel S, et al. Mol Imaging Biol. 2005 Jul-Aug;7(4):314-23. doi: 10.1007/s11307-005-0005-4. Mol Imaging Biol. 2005. PMID: 16080024

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