Tang YS - Search Results

1

Addressing the metabolic activation potential of new leads in drug discovery: a case study using ion trap mass spectrometry and tritium labeling techniques.

Samuel K, Yin W, Stearns RA, Tang YS, Chaudhary AG, Jewell JP, Lanza T Jr, Lin LS, Hagmann WK, Evans DC, Kumar S. Samuel K, et al. Among authors: tang ys. J Mass Spectrom. 2003 Feb;38(2):211-21. doi: 10.1002/jms.434. J Mass Spectrom. 2003. PMID: 12577288

2

Metabolic activation of a 1,3-disubstituted piperazine derivative: evidence for a novel ring contraction to an imidazoline.

Doss GA, Miller RR, Zhang Z, Teffera Y, Nargund RP, Palucki B, Park MK, Tang YS, Evans DC, Baillie TA, Stearns RA. Doss GA, et al. Among authors: tang ys. Chem Res Toxicol. 2005 Feb;18(2):271-6. doi: 10.1021/tx049711r. Chem Res Toxicol. 2005. PMID: 15720132

3

Evidence for the bioactivation of zomepirac and tolmetin by an oxidative pathway: identification of glutathione adducts in vitro in human liver microsomes and in vivo in rats.

Chen Q, Doss GA, Tung EC, Liu W, Tang YS, Braun MP, Didolkar V, Strauss JR, Wang RW, Stearns RA, Evans DC, Baillie TA, Tang W. Chen Q, et al. Among authors: tang w, tang ys. Drug Metab Dispos. 2006 Jan;34(1):145-51. doi: 10.1124/dmd.105.004341. Epub 2005 Oct 26. Drug Metab Dispos. 2006. PMID: 16251255

4

Disposition of L-732,531, a potent immunosuppressant, in rats and baboons.

Karanam BV, Miller RR, Colletti A, Montgomery T, Carey KD, Hawkins T, Tang YS, Lavin M, Stearns RA, Chiu SH, Vincent SH. Karanam BV, et al. Among authors: tang ys. Drug Metab Dispos. 1998 Oct;26(10):949-57. Drug Metab Dispos. 1998. PMID: 9763399

5

Regulation of energy homeostasis by bombesin receptor subtype-3: selective receptor agonists for the treatment of obesity.

Guan XM, Chen H, Dobbelaar PH, Dong Y, Fong TM, Gagen K, Gorski J, He S, Howard AD, Jian T, Jiang M, Kan Y, Kelly TM, Kosinski J, Lin LS, Liu J, Marsh DJ, Metzger JM, Miller R, Nargund RP, Palyha O, Shearman L, Shen Z, Stearns R, Strack AM, Stribling S, Tang YS, Wang SP, White A, Yu H, Reitman ML. Guan XM, et al. Among authors: tang ys. Cell Metab. 2010 Feb 3;11(2):101-12. doi: 10.1016/j.cmet.2009.12.008. Epub 2010 Jan 21. Cell Metab. 2010. PMID: 20096642 Free article.

6

3-Pyridyloxypropanolamine agonists of the beta 3 adrenergic receptor with improved pharmacokinetic properties.

Weber AE, Ok HO, Alvaro RF, Candelore MR, Cascieri MA, Chiu SH, Deng L, Forrest MJ, Hom GJ, Hutchins JE, Kao J, MacIntyre DE, Mathvink RJ, McLoughlin D, Miller RR, Newbold RC, Olah TV, Parmee ER, Perkins L, Stearns RA, Strader CD, Szumiloski J, Tang YS, Tota L, Fisher MH, et al. Weber AE, et al. Among authors: tang ys. Bioorg Med Chem Lett. 1998 Aug 18;8(16):2111-6. doi: 10.1016/s0960-894x(98)00381-3. Bioorg Med Chem Lett. 1998. PMID: 9873496

7

Identification of novel metabolites of pioglitazone in rat and dog.

Shen Z, Reed JR, Creighton M, Liu DQ, Tang YS, Hora DF, Feeney W, Szewczyk J, Bakhtiar R, Franklin RB, Vincent SH. Shen Z, et al. Among authors: tang ys. Xenobiotica. 2003 May;33(5):499-509. doi: 10.1080/0049825031000085951. Xenobiotica. 2003. PMID: 12746106

8

Characterization of a new class of potent inhibitors of the voltage-gated sodium channel Nav1.7.

Williams BS, Felix JP, Priest BT, Brochu RM, Dai K, Hoyt SB, London C, Tang YS, Duffy JL, Parsons WH, Kaczorowski GJ, Garcia ML. Williams BS, et al. Among authors: tang ys. Biochemistry. 2007 Dec 18;46(50):14693-703. doi: 10.1021/bi7018207. Epub 2007 Nov 21. Biochemistry. 2007. PMID: 18027973

9

Inhibitors of casein kinase 1 block the growth of Leishmania major promastigotes in vitro.

Allocco JJ, Donald R, Zhong T, Lee A, Tang YS, Hendrickson RC, Liberator P, Nare B. Allocco JJ, et al. Among authors: tang ys. Int J Parasitol. 2006 Oct;36(12):1249-59. doi: 10.1016/j.ijpara.2006.06.013. Epub 2006 Jul 20. Int J Parasitol. 2006. PMID: 16890941

10

Disposition of caspofungin, a novel antifungal agent, in mice, rats, rabbits, and monkeys.

Sandhu P, Xu X, Bondiskey PJ, Balani SK, Morris ML, Tang YS, Miller AR, Pearson PG. Sandhu P, et al. Among authors: tang ys. Antimicrob Agents Chemother. 2004 Apr;48(4):1272-80. doi: 10.1128/AAC.48.4.1272-1280.2004. Antimicrob Agents Chemother. 2004. PMID: 15047529 Free PMC article.

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