Gooderham N - Search Results

1

Investigation of interaction between N-acetyltransferase 2 and heterocyclic amines as potential risk factors for colorectal cancer.

Barrett JH, Smith G, Waxman R, Gooderham N, Lightfoot T, Garner RC, Augustsson K, Wolf CR, Bishop DT, Forman D; Colorectal Cancer Study Group. Barrett JH, et al. Among authors: gooderham n. Carcinogenesis. 2003 Feb;24(2):275-82. doi: 10.1093/carcin/24.2.275. Carcinogenesis. 2003. PMID: 12584178

2

Polymorphisms in the cytochrome P450 CYP1A2 gene (CYP1A2) in colorectal cancer patients and controls: allele frequencies, linkage disequilibrium and influence on caffeine metabolism.

Sachse C, Bhambra U, Smith G, Lightfoot TJ, Barrett JH, Scollay J, Garner RC, Boobis AR, Wolf CR, Gooderham NJ; Colorectal Cancer Study Group. Sachse C, et al. Br J Clin Pharmacol. 2003 Jan;55(1):68-76. doi: 10.1046/j.1365-2125.2003.01733.x. Br J Clin Pharmacol. 2003. PMID: 12534642 Free PMC article.

3

Expression of COX-2, NF-kappaB-p65, NF-kappaB-p50 and IKKalpha in malignant and adjacent normal human colorectal tissue.

Charalambous MP, Lightfoot T, Speirs V, Horgan K, Gooderham NJ. Charalambous MP, et al. Among authors: gooderham nj. Br J Cancer. 2009 Jul 7;101(1):106-15. doi: 10.1038/sj.bjc.6605120. Epub 2009 Jun 9. Br J Cancer. 2009. PMID: 19513071 Free PMC article.

4

Expression of cyclooxygenase-2 parallels expression of interleukin-1beta, interleukin-6 and NF-kappaB in human colorectal cancer.

Maihöfner C, Charalambous MP, Bhambra U, Lightfoot T, Geisslinger G, Gooderham NJ; Colorectal Cancer Group. Maihöfner C, et al. Carcinogenesis. 2003 Apr;24(4):665-71. doi: 10.1093/carcin/bgg006. Carcinogenesis. 2003. PMID: 12727794

5

Upregulation of cyclooxygenase-2 is accompanied by increased expression of nuclear factor-kappa B and I kappa B kinase-alpha in human colorectal cancer epithelial cells.

Charalambous MP, Maihöfner C, Bhambra U, Lightfoot T, Gooderham NJ; Colorectal Cancer Study Group. Charalambous MP, et al. Among authors: gooderham nj. Br J Cancer. 2003 May 19;88(10):1598-604. doi: 10.1038/sj.bjc.6600927. Br J Cancer. 2003. PMID: 12771929 Free PMC article.

6

Effect of cruciferous vegetable consumption on heterocyclic aromatic amine metabolism in man.

Murray S, Lake BG, Gray S, Edwards AJ, Springall C, Bowey EA, Williamson G, Boobis AR, Gooderham NJ. Murray S, et al. Among authors: gooderham nj. Carcinogenesis. 2001 Sep;22(9):1413-20. doi: 10.1093/carcin/22.9.1413. Carcinogenesis. 2001. PMID: 11532863

7

Interleukin-6 mediated upregulation of CYP1B1 and CYP2E1 in colorectal cancer involves DNA methylation, miR27b and STAT3.

Patel SA, Bhambra U, Charalambous MP, David RM, Edwards RJ, Lightfoot T, Boobis AR, Gooderham NJ. Patel SA, et al. Among authors: gooderham nj. Br J Cancer. 2014 Dec 9;111(12):2287-96. doi: 10.1038/bjc.2014.540. Epub 2014 Oct 21. Br J Cancer. 2014. PMID: 25333344 Free PMC article.

8

Mutational spectra of the dietary carcinogen 2-amino-1-methyl-6- phenylimidazo[4,5-b]pyridine(PhIP) at the Chinese hamsters hprt locus.

Yadollahi-Farsani M, Gooderham NJ, Davies DS, Boobis AR. Yadollahi-Farsani M, et al. Among authors: gooderham nj. Carcinogenesis. 1996 Apr;17(4):617-24. doi: 10.1093/carcin/17.4.617. Carcinogenesis. 1996. PMID: 8625468

9

Heterocyclic amines: evaluation of their role in diet associated human cancer.

Gooderham NJ, Murray S, Lynch AM, Edwards RJ, Yadollahi-Farsani M, Bratt C, Rich KJ, Zhao K, Murray BP, Bhadresa S, Crosbie SJ, Boobis AR, Davies DS. Gooderham NJ, et al. Br J Clin Pharmacol. 1996 Jul;42(1):91-8. doi: 10.1046/j.1365-2125.1996.37513.x. Br J Clin Pharmacol. 1996. PMID: 8807149 Free PMC article. Review.

10

Assessing human risk to heterocyclic amines.

Gooderham NJ, Murray S, Lynch AM, Yadollahi-Farsani M, Zhao K, Rich K, Boobis AR, Davies DS. Gooderham NJ, et al. Mutat Res. 1997 May 12;376(1-2):53-60. doi: 10.1016/s0027-5107(97)00025-0. Mutat Res. 1997. PMID: 9202738

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