Ohigashi Y - Search Results

1

Influenza B virus BM2 protein is an oligomeric integral membrane protein expressed at the cell surface.

Paterson RG, Takeda M, Ohigashi Y, Pinto LH, Lamb RA. Paterson RG, et al. Among authors: ohigashi y. Virology. 2003 Feb 1;306(1):7-17. doi: 10.1016/s0042-6822(02)00083-1. Virology. 2003. PMID: 12620792 Free article.

2

Influenza B virus BM2 protein has ion channel activity that conducts protons across membranes.

Mould JA, Paterson RG, Takeda M, Ohigashi Y, Venkataraman P, Lamb RA, Pinto LH. Mould JA, et al. Among authors: ohigashi y. Dev Cell. 2003 Jul;5(1):175-84. doi: 10.1016/s1534-5807(03)00190-4. Dev Cell. 2003. PMID: 12852861 Free article.

3

Identification of the pore-lining residues of the BM2 ion channel protein of influenza B virus.

Ma C, Soto CS, Ohigashi Y, Taylor A, Bournas V, Glawe B, Udo MK, Degrado WF, Lamb RA, Pinto LH. Ma C, et al. Among authors: ohigashi y. J Biol Chem. 2008 Jun 6;283(23):15921-31. doi: 10.1074/jbc.M710302200. Epub 2008 Apr 11. J Biol Chem. 2008. PMID: 18408016 Free PMC article.

4

Functional studies indicate amantadine binds to the pore of the influenza A virus M2 proton-selective ion channel.

Jing X, Ma C, Ohigashi Y, Oliveira FA, Jardetzky TS, Pinto LH, Lamb RA. Jing X, et al. Among authors: ohigashi y. Proc Natl Acad Sci U S A. 2008 Aug 5;105(31):10967-72. doi: 10.1073/pnas.0804958105. Epub 2008 Jul 31. Proc Natl Acad Sci U S A. 2008. PMID: 18669647 Free PMC article.

5

Identification of the functional core of the influenza A virus A/M2 proton-selective ion channel.

Ma C, Polishchuk AL, Ohigashi Y, Stouffer AL, Schön A, Magavern E, Jing X, Lear JD, Freire E, Lamb RA, DeGrado WF, Pinto LH. Ma C, et al. Among authors: ohigashi y. Proc Natl Acad Sci U S A. 2009 Jul 28;106(30):12283-8. doi: 10.1073/pnas.0905726106. Epub 2009 Jul 9. Proc Natl Acad Sci U S A. 2009. PMID: 19590009 Free PMC article.

6

An amantadine-sensitive chimeric BM2 ion channel of influenza B virus has implications for the mechanism of drug inhibition.

Ohigashi Y, Ma C, Jing X, Balannick V, Pinto LH, Lamb RA. Ohigashi Y, et al. Proc Natl Acad Sci U S A. 2009 Nov 3;106(44):18775-9. doi: 10.1073/pnas.0910584106. Epub 2009 Oct 19. Proc Natl Acad Sci U S A. 2009. PMID: 19841275 Free PMC article.

7

Design and pharmacological characterization of inhibitors of amantadine-resistant mutants of the M2 ion channel of influenza A virus.

Balannik V, Wang J, Ohigashi Y, Jing X, Magavern E, Lamb RA, Degrado WF, Pinto LH. Balannik V, et al. Among authors: ohigashi y. Biochemistry. 2009 Dec 22;48(50):11872-82. doi: 10.1021/bi9014488. Biochemistry. 2009. PMID: 19905033 Free PMC article.

8

The interplay of functional tuning, drug resistance, and thermodynamic stability in the evolution of the M2 proton channel from the influenza A virus.

Stouffer AL, Ma C, Cristian L, Ohigashi Y, Lamb RA, Lear JD, Pinto LH, DeGrado WF. Stouffer AL, et al. Among authors: ohigashi y. Structure. 2008 Jul;16(7):1067-76. doi: 10.1016/j.str.2008.04.011. Structure. 2008. PMID: 18611380 Free PMC article.

9

pH-induced conformational change of the influenza M2 protein C-terminal domain.

Nguyen PA, Soto CS, Polishchuk A, Caputo GA, Tatko CD, Ma C, Ohigashi Y, Pinto LH, DeGrado WF, Howard KP. Nguyen PA, et al. Among authors: ohigashi y. Biochemistry. 2008 Sep 23;47(38):9934-6. doi: 10.1021/bi801315m. Epub 2008 Aug 29. Biochemistry. 2008. PMID: 18754675 Free PMC article.

10

A new metal-binding site in photosynthetic bacterial reaction centers that modulates QA to QB electron transfer.

Utschig LM, Ohigashi Y, Thurnauer MC, Tiede DM. Utschig LM, et al. Among authors: ohigashi y. Biochemistry. 1998 Jun 9;37(23):8278-81. doi: 10.1021/bi980395n. Biochemistry. 1998. PMID: 9622479

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