Halford SE - Search Results

1

Germline mutations but not somatic changes at the MYH locus contribute to the pathogenesis of unselected colorectal cancers.

Halford SE, Rowan AJ, Lipton L, Sieber OM, Pack K, Thomas HJ, Hodgson SV, Bodmer WF, Tomlinson IP. Halford SE, et al. Am J Pathol. 2003 May;162(5):1545-8. doi: 10.1016/S0002-9440(10)64288-5. Am J Pathol. 2003. PMID: 12707038 Free PMC article.

2

CDX2 mutations do not account for juvenile polyposis or Peutz-Jeghers syndrome and occur infrequently in sporadic colorectal cancers.

Woodford-Richens KL, Halford S, Rowan A, Bevan S, Aaltonen LA, Wasan H, Bicknell D, Bodmer WF, Houlston RS, Tomlinson IP. Woodford-Richens KL, et al. Br J Cancer. 2001 May 18;84(10):1314-6. doi: 10.1054/bjoc.2001.1800. Br J Cancer. 2001. PMID: 11355940 Free PMC article.

3

SMAD4 mutations in colorectal cancer probably occur before chromosomal instability, but after divergence of the microsatellite instability pathway.

Woodford-Richens KL, Rowan AJ, Gorman P, Halford S, Bicknell DC, Wasan HS, Roylance RR, Bodmer WF, Tomlinson IP. Woodford-Richens KL, et al. Proc Natl Acad Sci U S A. 2001 Aug 14;98(17):9719-23. doi: 10.1073/pnas.171321498. Epub 2001 Jul 31. Proc Natl Acad Sci U S A. 2001. PMID: 11481457 Free PMC article.

4

Low-level microsatellite instability occurs in most colorectal cancers and is a nonrandomly distributed quantitative trait.

Halford S, Sasieni P, Rowan A, Wasan H, Bodmer W, Talbot I, Hawkins N, Ward R, Tomlinson I. Halford S, et al. Cancer Res. 2002 Jan 1;62(1):53-7. Cancer Res. 2002. PMID: 11782358

5

Does MSI-low exist?

Tomlinson I, Halford S, Aaltonen L, Hawkins N, Ward R. Tomlinson I, et al. J Pathol. 2002 May;197(1):6-13. doi: 10.1002/path.1071. J Pathol. 2002. PMID: 12081205 Review.

6

Genome-wide allelotyping of 104 Finnish colorectal cancers reveals an excess of allelic imbalance in chromosome 20q in familial cases.

Laiho P, Hienonen T, Karhu A, Lipton L, Aalto Y, Thomas HJ, Birkenkamp-Demtroder K, Hodgson S, Salovaara R, Mecklin JP, Järvinen H, Knuutila S, Halford S, Ørntoft TF, Tomlinson I, Launonen V, Houlston R, Aaltonen LA. Laiho P, et al. Oncogene. 2003 Apr 10;22(14):2206-14. doi: 10.1038/sj.onc.1206294. Oncogene. 2003. PMID: 12687022

7

MSI-low, a real phenomenon which varies in frequency among cancer types.

Halford SE, Sawyer EJ, Lambros MB, Gorman P, Macdonald ND, Talbot IC, Foulkes WD, Gillett CE, Barnes DM, Akslen LA, Lee K, Jacobs IJ, Hanby AM, Ganesan TS, Salvesen HB, Bodmer WF, Tomlinson IP, Roylance RR. Halford SE, et al. J Pathol. 2003 Nov;201(3):389-94. doi: 10.1002/path.1453. J Pathol. 2003. PMID: 14595750

8

Carcinogenesis in MYH-associated polyposis follows a distinct genetic pathway.

Lipton L, Halford SE, Johnson V, Novelli MR, Jones A, Cummings C, Barclay E, Sieber O, Sadat A, Bisgaard ML, Hodgson SV, Aaltonen LA, Thomas HJ, Tomlinson IP. Lipton L, et al. Among authors: halford se. Cancer Res. 2003 Nov 15;63(22):7595-9. Cancer Res. 2003. PMID: 14633673

9

Array comparative genomic hybridization analysis of colorectal cancer cell lines and primary carcinomas.

Douglas EJ, Fiegler H, Rowan A, Halford S, Bicknell DC, Bodmer W, Tomlinson IP, Carter NP. Douglas EJ, et al. Cancer Res. 2004 Jul 15;64(14):4817-25. doi: 10.1158/0008-5472.CAN-04-0328. Cancer Res. 2004. PMID: 15256451

10

Array-CGH analysis of microsatellite-stable, near-diploid bowel cancers and comparison with other types of colorectal carcinoma.

Jones AM, Douglas EJ, Halford SE, Fiegler H, Gorman PA, Roylance RR, Carter NP, Tomlinson IP. Jones AM, et al. Among authors: halford se. Oncogene. 2005 Jan 6;24(1):118-29. doi: 10.1038/sj.onc.1208194. Oncogene. 2005. PMID: 15531920

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