Ashrafian H - Search Results

1

Hypertrophic cardiomyopathy:a paradigm for myocardial energy depletion.

Ashrafian H, Redwood C, Blair E, Watkins H. Ashrafian H, et al. Trends Genet. 2003 May;19(5):263-8. doi: 10.1016/S0168-9525(03)00081-7. Trends Genet. 2003. PMID: 12711218 Review.

2

Disease pathways and novel therapeutic targets in hypertrophic cardiomyopathy.

Ashrafian H, McKenna WJ, Watkins H. Ashrafian H, et al. Circ Res. 2011 Jun 24;109(1):86-96. doi: 10.1161/CIRCRESAHA.111.242974. Circ Res. 2011. PMID: 21700950 Review.

3

Mutations in the gamma(2) subunit of AMP-activated protein kinase cause familial hypertrophic cardiomyopathy: evidence for the central role of energy compromise in disease pathogenesis.

Blair E, Redwood C, Ashrafian H, Oliveira M, Broxholme J, Kerr B, Salmon A, Ostman-Smith I, Watkins H. Blair E, et al. Among authors: ashrafian h. Hum Mol Genet. 2001 May 15;10(11):1215-20. doi: 10.1093/hmg/10.11.1215. Hum Mol Genet. 2001. PMID: 11371514

4

Mutant Muscle LIM Protein C58G causes cardiomyopathy through protein depletion.

Ehsan M, Kelly M, Hooper C, Yavari A, Beglov J, Bellahcene M, Ghataorhe K, Poloni G, Goel A, Kyriakou T, Fleischanderl K, Ehler E, Makeyev E, Lange S, Ashrafian H, Redwood C, Davies B, Watkins H, Gehmlich K. Ehsan M, et al. Among authors: ashrafian h. J Mol Cell Cardiol. 2018 Aug;121:287-296. doi: 10.1016/j.yjmcc.2018.07.248. Epub 2018 Jul 23. J Mol Cell Cardiol. 2018. PMID: 30048712 Free PMC article.

5

Reviews of translational medicine and genomics in cardiovascular disease: new disease taxonomy and therapeutic implications cardiomyopathies: therapeutics based on molecular phenotype.

Ashrafian H, Watkins H. Ashrafian H, et al. J Am Coll Cardiol. 2007 Mar 27;49(12):1251-64. doi: 10.1016/j.jacc.2006.10.073. Epub 2007 Mar 9. J Am Coll Cardiol. 2007. PMID: 17394955 Free article. Review.

6

Metabolic modulator perhexiline corrects energy deficiency and improves exercise capacity in symptomatic hypertrophic cardiomyopathy.

Abozguia K, Elliott P, McKenna W, Phan TT, Nallur-Shivu G, Ahmed I, Maher AR, Kaur K, Taylor J, Henning A, Ashrafian H, Watkins H, Frenneaux M. Abozguia K, et al. Among authors: ashrafian h. Circulation. 2010 Oct 19;122(16):1562-9. doi: 10.1161/CIRCULATIONAHA.109.934059. Epub 2010 Oct 4. Circulation. 2010. PMID: 20921440 Clinical Trial.

7

Inherited cardiomyopathies.

Watkins H, Ashrafian H, Redwood C. Watkins H, et al. Among authors: ashrafian h. N Engl J Med. 2011 Apr 28;364(17):1643-56. doi: 10.1056/NEJMra0902923. N Engl J Med. 2011. PMID: 21524215 Free article. Review. No abstract available.

8

Genetic cardiomyopathies causing heart failure.

Cahill TJ, Ashrafian H, Watkins H. Cahill TJ, et al. Among authors: ashrafian h. Circ Res. 2013 Aug 30;113(6):660-75. doi: 10.1161/CIRCRESAHA.113.300282. Circ Res. 2013. PMID: 23989711 Review.

9

Changes in the cardiac metabolome caused by perhexiline treatment in a mouse model of hypertrophic cardiomyopathy.

Gehmlich K, Dodd MS, Allwood JW, Kelly M, Bellahcene M, Lad HV, Stockenhuber A, Hooper C, Ashrafian H, Redwood CS, Carrier L, Dunn WB. Gehmlich K, et al. Among authors: ashrafian h. Mol Biosyst. 2015 Feb;11(2):564-73. doi: 10.1039/c4mb00594e. Mol Biosyst. 2015. PMID: 25437646

10

Myocardial dysfunction in hypertrophic cardiomyopathy.

Ashrafian H, Watkins H. Ashrafian H, et al. Circulation. 2001 Dec 18;104(25):E165. Circulation. 2001. PMID: 11748129 No abstract available.

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