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Lysine methyltransferase G9a is required for de novo DNA methylation and the establishment, but not the maintenance, of proviral silencing.
Leung DC, Dong KB, Maksakova IA, Goyal P, Appanah R, Lee S, Tachibana M, Shinkai Y, Lehnertz B, Mager DL, Rossi F, Lorincz MC. Leung DC, et al. Among authors: lehnertz b. Proc Natl Acad Sci U S A. 2011 Apr 5;108(14):5718-23. doi: 10.1073/pnas.1014660108. Epub 2011 Mar 22. Proc Natl Acad Sci U S A. 2011. PMID: 21427230 Free PMC article.
The methyltransferase G9a regulates HoxA9-dependent transcription in AML.
Lehnertz B, Pabst C, Su L, Miller M, Liu F, Yi L, Zhang R, Krosl J, Yung E, Kirschner J, Rosten P, Underhill TM, Jin J, Hébert J, Sauvageau G, Humphries RK, Rossi FM. Lehnertz B, et al. Genes Dev. 2014 Feb 15;28(4):317-27. doi: 10.1101/gad.236794.113. Genes Dev. 2014. PMID: 24532712 Free PMC article.
Control of the hippo pathway by Set7-dependent methylation of Yap.
Oudhoff MJ, Freeman SA, Couzens AL, Antignano F, Kuznetsova E, Min PH, Northrop JP, Lehnertz B, Barsyte-Lovejoy D, Vedadi M, Arrowsmith CH, Nishina H, Gold MR, Rossi FM, Gingras AC, Zaph C. Oudhoff MJ, et al. Among authors: lehnertz b. Dev Cell. 2013 Jul 29;26(2):188-94. doi: 10.1016/j.devcel.2013.05.025. Epub 2013 Jul 11. Dev Cell. 2013. PMID: 23850191 Free article.
Genetic characterization of ABT-199 sensitivity in human AML.
Bisaillon R, Moison C, Thiollier C, Krosl J, Bordeleau ME, Lehnertz B, Lavallée VP, MacRae T, Mayotte N, Labelle C, Boucher G, Spinella JF, Boivin I, D'Angelo G, Lavallée S, Marinier A, Lemieux S, Hébert J, Sauvageau G. Bisaillon R, et al. Among authors: lehnertz b. Leukemia. 2020 Jan;34(1):63-74. doi: 10.1038/s41375-019-0485-x. Epub 2019 Jul 12. Leukemia. 2020. PMID: 31300747
Vesicular trafficking is a key determinant of the statin response in acute myeloid leukemia.
Krosl J, Bordeleau ME, Moison C, MacRae T, Boivin I, Mayotte N, Gracias D, Baccelli I, Lavallée VP, Bisaillon R, Lehnertz B, Mendoza-Sanchez R, Ruel R, Bertomeu T, Coulombe-Huntington J, Boucher G, Noronha N, Pabst C, Tyers M, Gendron P, Lemieux S, Barabé F, Marinier A, Hébert J, Sauvageau G. Krosl J, et al. Among authors: lehnertz b. Blood Adv. 2022 Jan 25;6(2):509-514. doi: 10.1182/bloodadvances.2021006047. Blood Adv. 2022. PMID: 34731885 Free PMC article.
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