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Glucolipotoxicity alters lipid partitioning and causes mitochondrial dysfunction, cholesterol, and ceramide deposition and reactive oxygen species production in INS832/13 ss-cells.
El-Assaad W, Joly E, Barbeau A, Sladek R, Buteau J, Maestre I, Pepin E, Zhao S, Iglesias J, Roche E, Prentki M. El-Assaad W, et al. Among authors: prentki m. Endocrinology. 2010 Jul;151(7):3061-73. doi: 10.1210/en.2009-1238. Epub 2010 May 5. Endocrinology. 2010. PMID: 20444946
Islet beta cell failure in type 2 diabetes.
Prentki M, Nolan CJ. Prentki M, et al. J Clin Invest. 2006 Jul;116(7):1802-12. doi: 10.1172/JCI29103. J Clin Invest. 2006. PMID: 16823478 Free PMC article. Review.
The islet beta-cell: fuel responsive and vulnerable.
Nolan CJ, Prentki M. Nolan CJ, et al. Among authors: prentki m. Trends Endocrinol Metab. 2008 Oct;19(8):285-91. doi: 10.1016/j.tem.2008.07.006. Epub 2008 Sep 6. Trends Endocrinol Metab. 2008. PMID: 18774732 Review.
194 results