Sequence analyses and comparative modeling of fly and worm fibroblast growth factor receptors indicate that the determinants for FGF and heparin binding are retained in evolution.
Nagendra HG, Harrington AE, Harmer NJ, Pellegrini L, Blundell TL, Burke DF.
Nagendra HG, et al. Among authors: pellegrini l.
FEBS Lett. 2001 Jul 13;501(1):51-8. doi: 10.1016/s0014-5793(01)02603-5.
FEBS Lett. 2001.
PMID: 11457455
Free article.
We have analysed the sequences of worm and fly FGFs and FGFRs and used the recently determined crystal structure of the human FGF1-FGFR2-heparin ternary complex [Pellegrini, L., Burke, D.F., von Delft, F., Mulloy, B. and Blundell, T.L. (2000) Nature 407, 1029 …
We have analysed the sequences of worm and fly FGFs and FGFRs and used the recently determined crystal structure of the human FGF1-FGFR2-hep …