Zhang M - Search Results

1

Synthesis and biological characterization of 1-methyl-1,2,5,6-tetrahydropyridyl-1,2,5-thiadiazole derivatives as muscarinic agonists for the treatment of neurological disorders.

Cao Y, Zhang M, Wu C, Lee S, Wroblewski ME, Whipple T, Nagy PI, Takács-Novák K, Balázs A, Torös S, Messer WS Jr. Cao Y, et al. Among authors: zhang m. J Med Chem. 2003 Sep 25;46(20):4273-86. doi: 10.1021/jm0301235. J Med Chem. 2003. PMID: 13678406

2

Optimization of benzoxazole-based inhibitors of Cryptosporidium parvum inosine 5'-monophosphate dehydrogenase.

Gorla SK, Kavitha M, Zhang M, Chin JE, Liu X, Striepen B, Makowska-Grzyska M, Kim Y, Joachimiak A, Hedstrom L, Cuny GD. Gorla SK, et al. Among authors: zhang m. J Med Chem. 2013 May 23;56(10):4028-43. doi: 10.1021/jm400241j. Epub 2013 May 13. J Med Chem. 2013. PMID: 23668331 Free PMC article.

3

Triazole inhibitors of Cryptosporidium parvum inosine 5'-monophosphate dehydrogenase.

Maurya SK, Gollapalli DR, Kirubakaran S, Zhang M, Johnson CR, Benjamin NN, Hedstrom L, Cuny GD. Maurya SK, et al. Among authors: zhang m. J Med Chem. 2009 Aug 13;52(15):4623-30. doi: 10.1021/jm900410u. J Med Chem. 2009. PMID: 19624136 Free PMC article.

4

Selective and potent urea inhibitors of cryptosporidium parvum inosine 5'-monophosphate dehydrogenase.

Gorla SK, Kavitha M, Zhang M, Liu X, Sharling L, Gollapalli DR, Striepen B, Hedstrom L, Cuny GD. Gorla SK, et al. Among authors: zhang m. J Med Chem. 2012 Sep 13;55(17):7759-71. doi: 10.1021/jm3007917. Epub 2012 Sep 5. J Med Chem. 2012. PMID: 22950983 Free PMC article.

5

Repurposing cryptosporidium inosine 5'-monophosphate dehydrogenase inhibitors as potential antibacterial agents.

Mandapati K, Gorla SK, House AL, McKenney ES, Zhang M, Rao SN, Gollapalli DR, Mann BJ, Goldberg JB, Cuny GD, Glomski IJ, Hedstrom L. Mandapati K, et al. Among authors: zhang m. ACS Med Chem Lett. 2014 Jun 10;5(8):846-50. doi: 10.1021/ml500203p. eCollection 2014 Aug 14. ACS Med Chem Lett. 2014. PMID: 25147601 Free PMC article.

6

Structure-activity relationship study of selective benzimidazole-based inhibitors of Cryptosporidium parvum IMPDH.

Kirubakaran S, Gorla SK, Sharling L, Zhang M, Liu X, Ray SS, Macpherson IS, Striepen B, Hedstrom L, Cuny GD. Kirubakaran S, et al. Among authors: zhang m. Bioorg Med Chem Lett. 2012 Mar 1;22(5):1985-8. doi: 10.1016/j.bmcl.2012.01.029. Epub 2012 Jan 24. Bioorg Med Chem Lett. 2012. PMID: 22310229 Free PMC article.

7

Synthesis, in vitro evaluation and cocrystal structure of 4-oxo-[1]benzopyrano[4,3-c]pyrazole Cryptosporidium parvum inosine 5'-monophosphate dehydrogenase (CpIMPDH) inhibitors.

Sun Z, Khan J, Makowska-Grzyska M, Zhang M, Cho JH, Suebsuwong C, Vo P, Gollapalli DR, Kim Y, Joachimiak A, Hedstrom L, Cuny GD. Sun Z, et al. Among authors: zhang m. J Med Chem. 2014 Dec 26;57(24):10544-50. doi: 10.1021/jm501527z. Epub 2014 Dec 4. J Med Chem. 2014. PMID: 25474504 Free PMC article.

8

Phthalazinone inhibitors of inosine-5'-monophosphate dehydrogenase from Cryptosporidium parvum.

Johnson CR, Gorla SK, Kavitha M, Zhang M, Liu X, Striepen B, Mead JR, Cuny GD, Hedstrom L. Johnson CR, et al. Among authors: zhang m. Bioorg Med Chem Lett. 2013 Feb 15;23(4):1004-7. doi: 10.1016/j.bmcl.2012.12.037. Epub 2012 Dec 27. Bioorg Med Chem Lett. 2013. PMID: 23324406 Free PMC article.

9

Expanding Benzoxazole-Based Inosine 5'-Monophosphate Dehydrogenase (IMPDH) Inhibitor Structure-Activity As Potential Antituberculosis Agents.

Chacko S, Boshoff HIM, Singh V, Ferraris DM, Gollapalli DR, Zhang M, Lawson AP, Pepi MJ, Joachimiak A, Rizzi M, Mizrahi V, Cuny GD, Hedstrom L. Chacko S, et al. Among authors: zhang m. J Med Chem. 2018 Jun 14;61(11):4739-4756. doi: 10.1021/acs.jmedchem.7b01839. Epub 2018 May 30. J Med Chem. 2018. PMID: 29746130 Free PMC article.

10

Mycophenolic anilides as broad specificity inosine-5'-monophosphate dehydrogenase (IMPDH) inhibitors.

Lee S, Ku AF, Vippila MR, Wang Y, Zhang M, Wang X, Hedstrom L, Cuny GD. Lee S, et al. Among authors: zhang m. Bioorg Med Chem Lett. 2020 Dec 15;30(24):127543. doi: 10.1016/j.bmcl.2020.127543. Epub 2020 Sep 12. Bioorg Med Chem Lett. 2020. PMID: 32931912 Free PMC article.

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