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Page 1
Functional roles of Akt signaling in mouse skin tumorigenesis.
Segrelles C, Ruiz S, Perez P, Murga C, Santos M, Budunova IV, Martínez J, Larcher F, Slaga TJ, Gutkind JS, Jorcano JL, Paramio JM. Segrelles C, et al. Oncogene. 2002 Jan 3;21(1):53-64. doi: 10.1038/sj.onc.1205032. Oncogene. 2002. PMID: 11791176
Deregulated activity of Akt in epithelial basal cells induces spontaneous tumors and heightened sensitivity to skin carcinogenesis.
Segrelles C, Lu J, Hammann B, Santos M, Moral M, Cascallana JL, Lara MF, Rho O, Carbajal S, Traag J, Beltrán L, Martínez-Cruz AB, García-Escudero R, Lorz C, Ruiz S, Bravo A, Paramio JM, DiGiovanni J. Segrelles C, et al. Cancer Res. 2007 Nov 15;67(22):10879-88. doi: 10.1158/0008-5472.CAN-07-2564. Cancer Res. 2007. PMID: 18006833
IKKβ-Mediated Resistance to Skin Cancer Development Is Ink4a/Arf-Dependent.
Page A, Bravo A, Suarez-Cabrera C, Alameda JP, Casanova ML, Lorz C, Segrelles C, Segovia JC, Paramio JM, Navarro M, Ramirez A. Page A, et al. Among authors: segrelles c. Mol Cancer Res. 2017 Sep;15(9):1255-1264. doi: 10.1158/1541-7786.MCR-17-0157. Epub 2017 Jun 5. Mol Cancer Res. 2017. PMID: 28584022
Inhibition of protein kinase B (PKB) and PKCzeta mediates keratin K10-induced cell cycle arrest.
Paramio JM, Segrelles C, Ruiz S, Jorcano JL. Paramio JM, et al. Among authors: segrelles c. Mol Cell Biol. 2001 Nov;21(21):7449-59. doi: 10.1128/MCB.21.21.7449-7459.2001. Mol Cell Biol. 2001. PMID: 11585925 Free PMC article.
We recently demonstrated that expression of keratin K10 or K16 may regulate the phosphorylation of the retinoblastoma protein (pRb), inhibiting (K10) or stimulating (K16) cell proliferation (J. M. Paramio, M. L. Casanova, C. Segrelles, S. Mittnacht, E. B. Lane, and …
We recently demonstrated that expression of keratin K10 or K16 may regulate the phosphorylation of the retinoblastoma protein (pRb), inhibit …
55 results