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Association of intercellular adhesion molecule-1 gene with type 1 diabetes.
Nejentsev S, Guja C, McCormack R, Cooper J, Howson JM, Nutland S, Rance H, Walker N, Undlien D, Ronningen KS, Tuomilehto-Wolf E, Tuomilehto J, Ionescu-Tirgoviste C, Gale EA, Bingley PJ, Gillespie KM, Savage DA, Carson DJ, Patterson CC, Maxwell AP, Todd JA. Nejentsev S, et al. Among authors: walker n. Lancet. 2003 Nov 22;362(9397):1723-4. doi: 10.1016/S0140-6736(03)14847-7. Lancet. 2003. PMID: 14643123
Testing the possible negative association of type 1 diabetes and atopic disease by analysis of the interleukin 4 receptor gene.
Maier LM, Twells RC, Howson JM, Lam AC, Clayton DG, Smyth DJ, Savage D, Carson D, Patterson CC, Smink LJ, Walker NM, Burren OS, Nutland S, Rance H, Tuomilehto-Wolf E, Tuomilehto J, Guja C, Ionescu-Tirgoviste C, Undlien DE, Rønningen KS, Cucca F, Todd JA. Maier LM, et al. Among authors: walker nm. Genes Immun. 2003 Oct;4(7):469-75. doi: 10.1038/sj.gene.6364007. Genes Immun. 2003. PMID: 14551599
Replication of an association between the lymphoid tyrosine phosphatase locus (LYP/PTPN22) with type 1 diabetes, and evidence for its role as a general autoimmunity locus.
Smyth D, Cooper JD, Collins JE, Heward JM, Franklyn JA, Howson JM, Vella A, Nutland S, Rance HE, Maier L, Barratt BJ, Guja C, Ionescu-Tîrgoviste C, Savage DA, Dunger DB, Widmer B, Strachan DP, Ring SM, Walker N, Clayton DG, Twells RC, Gough SC, Todd JA. Smyth D, et al. Among authors: walker n. Diabetes. 2004 Nov;53(11):3020-3. doi: 10.2337/diabetes.53.11.3020. Diabetes. 2004. PMID: 15504986
No association of multiple type 2 diabetes loci with type 1 diabetes.
Raj SM, Howson JM, Walker NM, Cooper JD, Smyth DJ, Field SF, Stevens HE, Todd JA. Raj SM, et al. Among authors: walker nm. Diabetologia. 2009 Oct;52(10):2109-16. doi: 10.1007/s00125-009-1391-y. Epub 2009 May 20. Diabetologia. 2009. PMID: 19455305 Free PMC article.
Analysis of 55 autoimmune disease and type II diabetes loci: further confirmation of chromosomes 4q27, 12q13.2 and 12q24.13 as type I diabetes loci, and support for a new locus, 12q13.3-q14.1.
Cooper JD, Walker NM, Healy BC, Smyth DJ, Downes K, Todd JA; Type I Diabetes Genetics Consortium. Cooper JD, et al. Among authors: walker nm. Genes Immun. 2009 Dec;10 Suppl 1(Suppl 1):S95-120. doi: 10.1038/gene.2009.98. Genes Immun. 2009. PMID: 19956108 Free PMC article.
Parameters for reliable results in genetic association studies in common disease.
Dahlman I, Eaves IA, Kosoy R, Morrison VA, Heward J, Gough SC, Allahabadia A, Franklyn JA, Tuomilehto J, Tuomilehto-Wolf E, Cucca F, Guja C, Ionescu-Tirgoviste C, Stevens H, Carr P, Nutland S, McKinney P, Shield JP, Wang W, Cordell HJ, Walker N, Todd JA, Concannon P. Dahlman I, et al. Among authors: walker n. Nat Genet. 2002 Feb;30(2):149-50. doi: 10.1038/ng825. Epub 2002 Jan 22. Nat Genet. 2002. PMID: 11799396
Construction and analysis of tag single nucleotide polymorphism maps for six human-mouse orthologous candidate genes in type 1 diabetes.
Maier LM, Smyth DJ, Vella A, Payne F, Cooper JD, Pask R, Lowe C, Hulme J, Smink LJ, Fraser H, Moule C, Hunter KM, Chamberlain G, Walker N, Nutland S, Undlien DE, Rønningen KS, Guja C, Ionescu-Tîrgoviste C, Savage DA, Strachan DP, Peterson LB, Todd JA, Wicker LS, Twells RC. Maier LM, et al. Among authors: walker n. BMC Genet. 2005 Feb 18;6:9. doi: 10.1186/1471-2156-6-9. BMC Genet. 2005. PMID: 15720714 Free PMC article.
1,818 results