Corbley MJ - Search Results

1

Successful shape-based virtual screening: the discovery of a potent inhibitor of the type I TGFbeta receptor kinase (TbetaRI).

Singh J, Chuaqui CE, Boriack-Sjodin PA, Lee WC, Pontz T, Corbley MJ, Cheung HK, Arduini RM, Mead JN, Newman MN, Papadatos JL, Bowes S, Josiah S, Ling LE. Singh J, et al. Among authors: corbley mj. Bioorg Med Chem Lett. 2003 Dec 15;13(24):4355-9. doi: 10.1016/j.bmcl.2003.09.028. Bioorg Med Chem Lett. 2003. PMID: 14643325

2

SM16, an orally active TGF-beta type I receptor inhibitor prevents myofibroblast induction and vascular fibrosis in the rat carotid injury model.

Fu K, Corbley MJ, Sun L, Friedman JE, Shan F, Papadatos JL, Costa D, Lutterodt F, Sweigard H, Bowes S, Choi M, Boriack-Sjodin PA, Arduini RM, Sun D, Newman MN, Zhang X, Mead JN, Chuaqui CE, Cheung HK, Zhang X, Cornebise M, Carter MB, Josiah S, Singh J, Lee WC, Gill A, Ling LE. Fu K, et al. Among authors: corbley mj. Arterioscler Thromb Vasc Biol. 2008 Apr;28(4):665-71. doi: 10.1161/ATVBAHA.107.158030. Epub 2008 Jan 17. Arterioscler Thromb Vasc Biol. 2008. PMID: 18202322

3

A novel small-molecule inhibitor of transforming growth factor beta type I receptor kinase (SM16) inhibits murine mesothelioma tumor growth in vivo and prevents tumor recurrence after surgical resection.

Suzuki E, Kim S, Cheung HK, Corbley MJ, Zhang X, Sun L, Shan F, Singh J, Lee WC, Albelda SM, Ling LE. Suzuki E, et al. Among authors: corbley mj. Cancer Res. 2007 Mar 1;67(5):2351-9. doi: 10.1158/0008-5472.CAN-06-2389. Cancer Res. 2007. PMID: 17332368

4

Small molecular inhibitor of transforming growth factor-beta protects against development of radiation-induced lung injury.

Anscher MS, Thrasher B, Zgonjanin L, Rabbani ZN, Corbley MJ, Fu K, Sun L, Lee WC, Ling LE, Vujaskovic Z. Anscher MS, et al. Among authors: corbley mj. Int J Radiat Oncol Biol Phys. 2008 Jul 1;71(3):829-37. doi: 10.1016/j.ijrobp.2008.02.046. Epub 2008 Apr 12. Int J Radiat Oncol Biol Phys. 2008. PMID: 18411002

5

Postnatal recapitulation of embryonic hedgehog pathway in response to skeletal muscle ischemia.

Pola R, Ling LE, Aprahamian TR, Barban E, Bosch-Marce M, Curry C, Corbley M, Kearney M, Isner JM, Losordo DW. Pola R, et al. Circulation. 2003 Jul 29;108(4):479-85. doi: 10.1161/01.CIR.0000080338.60981.FA. Epub 2003 Jul 14. Circulation. 2003. PMID: 12860919

6

Systemic blockade of transforming growth factor-beta signaling augments the efficacy of immunogene therapy.

Kim S, Buchlis G, Fridlender ZG, Sun J, Kapoor V, Cheng G, Haas A, Cheung HK, Zhang X, Corbley M, Kaiser LR, Ling L, Albelda SM. Kim S, et al. Cancer Res. 2008 Dec 15;68(24):10247-56. doi: 10.1158/0008-5472.CAN-08-1494. Cancer Res. 2008. PMID: 19074893 Free PMC article.

7

The morphogen Sonic hedgehog is an indirect angiogenic agent upregulating two families of angiogenic growth factors.

Pola R, Ling LE, Silver M, Corbley MJ, Kearney M, Blake Pepinsky R, Shapiro R, Taylor FR, Baker DP, Asahara T, Isner JM. Pola R, et al. Among authors: corbley mj. Nat Med. 2001 Jun;7(6):706-11. doi: 10.1038/89083. Nat Med. 2001. PMID: 11385508

8

A strategy for screening anti-tumor drugs utilizing oncogenes encoded in retroviral vectors.

Corbley MJ, Cherington V, Traxler PM, Lydon NB, Roberts TM. Corbley MJ, et al. Int J Cancer. 1996 Jun 11;66(6):753-9. doi: 10.1002/(SICI)1097-0215(19960611)66:6<753::AID-IJC8>3.0.CO;2-Z. Int J Cancer. 1996. PMID: 8647645 Free article.

9

A phase I clinical trial of single-dose intrapleural IFN-beta gene transfer for malignant pleural mesothelioma and metastatic pleural effusions: high rate of antitumor immune responses.

Sterman DH, Recio A, Carroll RG, Gillespie CT, Haas A, Vachani A, Kapoor V, Sun J, Hodinka R, Brown JL, Corbley MJ, Parr M, Ho M, Pastan I, Machuzak M, Benedict W, Zhang XQ, Lord EM, Litzky LA, Heitjan DF, June CH, Kaiser LR, Vonderheide RH, Albelda SM, Kanther M. Sterman DH, et al. Among authors: corbley mj. Clin Cancer Res. 2007 Aug 1;13(15 Pt 1):4456-66. doi: 10.1158/1078-0432.CCR-07-0403. Clin Cancer Res. 2007. PMID: 17671130 Clinical Trial.

10

Rapid regeneration of virus from cells infected with a retroviral vector.

Corbley MJ, Cherington V, Feig LA, Cooper GM, Roberts TM. Corbley MJ, et al. Biotechniques. 1994 Dec;17(6):1102-3, 1106-9. Biotechniques. 1994. PMID: 7873180

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